Jennifer Nichols
Jennifer Nichols
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Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4
J Nichols, B Zevnik, K Anastassiadis, H Niwa, D Klewe-Nebenius, ...
Cell 95 (3), 379-391, 1998
Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells
I Chambers, D Colby, M Robertson, J Nichols, S Lee, S Tweedie, A Smith
Cell 113 (5), 643-655, 2003
The ground state of embryonic stem cell self-renewal
QL Ying, J Wray, J Nichols, L Batlle-Morera, B Doble, J Woodgett, ...
nature 453 (7194), 519-523, 2008
BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3
QL Ying, J Nichols, I Chambers, A Smith
Cell 115 (3), 281-292, 2003
Changing potency by spontaneous fusion
QL Ying, J Nichols, EP Evans, AG Smith
Nature 416 (6880), 545-548, 2002
Naive and primed pluripotent states
J Nichols, A Smith
Cell stem cell 4 (6), 487-492, 2009
Nanog safeguards pluripotency and mediates germline development
I Chambers, J Silva, D Colby, J Nichols, B Nijmeijer, M Robertson, ...
Nature 450 (7173), 1230-1234, 2007
Nanog is the gateway to the pluripotent ground state
J Silva, J Nichols, TW Theunissen, G Guo, AL van Oosten, O Barrandon, ...
Cell 138 (4), 722-737, 2009
Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
E Volz, V Hill, JT McCrone, A Price, D Jorgensen, Á O’Toole, J Southgate, ...
Cell 184 (1), 64-75. e11, 2021
Promotion of reprogramming to ground state pluripotency by signal inhibition
J Silva, O Barrandon, J Nichols, J Kawaguchi, TW Theunissen, A Smith
PLoS biology 6 (10), e253, 2008
Resetting transcription factor control circuitry toward ground-state pluripotency in human
Y Takashima, G Guo, R Loos, J Nichols, G Ficz, F Krueger, D Oxley, ...
Cell 158 (6), 1254-1269, 2014
The transcriptional and epigenomic foundations of ground state pluripotency
H Marks, T Kalkan, R Menafra, S Denissov, K Jones, H Hofemeister, ...
Cell 149 (3), 590-604, 2012
Klf4 reverts developmentally programmed restriction of ground state pluripotency
G Guo, J Yang, J Nichols, JS Hall, I Eyres, W Mansfield, A Smith
Oxford University Press for The Company of Biologists Limited 136 (7), 1063-1069, 2009
Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort study
KA Twohig, T Nyberg, A Zaidi, S Thelwall, MA Sinnathamby, S Aliabadi, ...
The Lancet Infectious Diseases 22 (1), 35-42, 2022
Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells
T Burdon, C Stracey, I Chambers, J Nichols, A Smith
Developmental biology 210 (1), 30-43, 1999
A single-cell molecular map of mouse gastrulation and early organogenesis
B Pijuan-Sala, JA Griffiths, C Guibentif, TW Hiscock, W Jawaid, ...
Nature 566 (7745), 490-495, 2019
Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
J Nichols, J Silva, M Roode, A Smith
Development 136 (19), 3215-3222, 2009
Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells
T Kalmar, C Lim, P Hayward, S Muñoz-Descalzo, J Nichols, ...
PLoS biology 7 (7), e1000149, 2009
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
EC Thomson, LE Rosen, JG Shepherd, R Spreafico, A da Silva Filipe, ...
Cell 184 (5), 1171-1187. e20, 2021
Efficacy and safety of nerinetide for the treatment of acute ischaemic stroke (ESCAPE-NA1): a multicentre, double-blind, randomised controlled trial
MD Hill, M Goyal, BK Menon, RG Nogueira, RA McTaggart, AM Demchuk, ...
The Lancet 395 (10227), 878-887, 2020
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