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Man Kyu Shim
Man Kyu Shim
Senior Research Scientist, Korea Institute of Science and Technology (KIST)
kist.re.kr의 이메일 확인됨
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Carrier-free nanoparticles of cathepsin B-cleavable peptide-conjugated doxorubicin prodrug for cancer targeting therapy
MK Shim, J Park, HY Yoon, S Lee, W Um, JH Kim, SW Kang, JW Seo, ...
Journal of Controlled Release 294 (28), 376-389, 2019
1202019
Necroptosis‐Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy
W Um, H Ko, DG You, S Lim, G Kwak, MK Shim, S Yang, J Lee, Y Song, ...
Advanced Materials 32 (16), 1907953, 2020
1142020
Recent advances and challenges of repurposing nanoparticle-based drug delivery systems to enhance cancer immunotherapy
S Lim, J Park, MK Shim, W Um, HY Yoon, JH Ryu, DK Lim, K Kim
Theranostics 9 (25), 7906, 2019
1032019
Visible-Light-Triggered Prodrug Nanoparticles Combine Chemotherapy and Photodynamic Therapy to Potentiate Checkpoint Blockade Cancer Immunotherapy
J Choi, MK Shim, S Yang, HS Hwang, H Cho, J Kim, WS Yun, Y Moon, ...
ACS nano 15 (7), 12086–12098, 2021
992021
Cathepsin B‐specific metabolic precursor for in vivo tumor‐specific fluorescence imaging
MK Shim, HY Yoon, JH Ryu, H Koo, S Lee, JH Park, JH Kim, S Lee, ...
Angewandte Chemie 128 (47), 14918-14923, 2016
912016
Cancer-activated doxorubicin prodrug nanoparticles induce preferential immune response with minimal doxorubicin-related toxicity
S Yang, MK Shim, WJ Kim, J Choi, GH Nam, J Kim, J Kim, Y Moon, ...
Biomaterials 272, 120791, 2021
892021
Tumor-activated carrier-free prodrug nanoparticles for targeted cancer Immunotherapy: Preclinical evidence for safe and effective drug delivery
MK Shim, S Yang, IC Sun, K Kim
Advanced Drug Delivery Reviews, 114177, 2022
752022
Cancer-specific drug-drug nanoparticles of pro-apoptotic and cathepsin B-cleavable peptide-conjugated doxorubicin for drug-resistant cancer therapy
MK Shim, Y Moon, S Yang, J Kim, H Cho, S Lim, HY Yoon, JK Seong, ...
Biomaterials 261, 120347, 2020
732020
Effects of tumor microenvironments on targeted delivery of glycol chitosan nanoparticles
JY Yhee, S Jeon, HY Yoon, MK Shim, H Ko, J Min, JH Na, H Chang, ...
Journal of Controlled Release 267, 223-231, 2017
682017
In situ one-step fluorescence labeling strategy of exosomes via bioorthogonal click chemistry for real-time exosome tracking in vitro and in vivo
S Song, MK Shim, S Lim, Y Moon, S Yang, J Kim, Y Hong, HY Yoon, ...
Bioconjugate Chemistry 31 (5), 1562–1574, 2020
642020
Caspase-3/-7-specific metabolic precursor for bioorthogonal tracking of tumor apoptosis
MK Shim, HY Yoon, S Lee, MK Jo, J Park, JH Kim, SY Jeong, IC Kwon, ...
Scientific reports 7 (1), 16635, 2017
592017
Anti-PD-L1 peptide-conjugated prodrug nanoparticles for targeted cancer immunotherapy combining PD-L1 blockade with immunogenic cell death
Y Moon, MK Shim, J Choi, S Yang, J Kim, WS Yun, H Cho, JY Park, Y Kim, ...
Theranostics 12 (5), 1999, 2022
552022
Visible light-induced apoptosis activatable nanoparticles of photosensitizer-DEVD-anticancer drug conjugate for targeted cancer therapy
W Um, J Park, H Ko, S Lim, HY Yoon, MK Shim, S Lee, YJ Ko, MJ Kim, ...
Biomaterials 224, 119494, 2019
542019
Nano-sized metabolic precursors for heterogeneous tumor-targeting strategy using bioorthogonal click chemistry in vivo
S Lee, S Jung, H Koo, JH Na, HY Yoon, MK Shim, J Park, JH Kim, S Lee, ...
Biomaterials 148, 1-15, 2017
542017
Hydrophobically modified polysaccharide-based on polysialic acid nanoparticles as carriers for anticancer drugs
B Jung, MK Shim, MJ Park, EH Jang, HY Yoon, K Kim, JH Kim
International Journal of Pharmaceutics 520 (1-2), 111-118, 2017
522017
Artificial chemical reporter targeting strategy using bioorthogonal click reaction for improving active-targeting efficiency of tumor
HY Yoon, ML Shin, MK Shim, S Lee, JH Na, H Koo, H Lee, JH Kim, ...
Molecular pharmaceutics 14 (5), 1558-1570, 2017
462017
Heat shock responsive drug delivery system based on mesoporous silica nanoparticles coated with temperature sensitive gatekeeper
IH Cho, MK Shim, B Jung, EH Jang, MJ Park, HC Kang, JH Kim
Microporous and Mesoporous Materials 253, 96-101, 2017
452017
Combination of cancer-specific prodrug nanoparticle with Bcl-2 inhibitor to overcome acquired drug resistance
J Kim, MK Shim, S Yang, Y Moon, S Song, J Choi, J Kim, K Kim
Journal of controlled release 330, 920-932, 2021
442021
Doxorubicin-loaded PLGA nanoparticles for cancer therapy: molecular weight effect of PLGA in doxorubicin release for controlling immunogenic cell death
Y Choi, HY Yoon, J Kim, S Yang, J Lee, JW Choi, Y Moon, J Kim, S Lim, ...
Pharmaceutics 12 (12), 1165, 2020
432020
Emerging albumin-binding anticancer drugs for tumor-targeted drug delivery: current understandings and clinical translation
H Cho, SI Jeon, CH Ahn, MK Shim, K Kim
Pharmaceutics 14 (4), 728, 2022
382022
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학술자료 1–20