| HIV-1 broadly neutralizing antibody precursor B cells revealed by germline-targeting immunogen JG Jardine, DW Kulp, C Havenar-Daughton, A Sarkar, B Briney, D Sok, ... Science 351 (6280), 1458-1463, 2016 | 425 | 2016 |
| Tailored immunogens direct affinity maturation toward HIV neutralizing antibodies B Briney, D Sok, JG Jardine, DW Kulp, P Skog, S Menis, R Jacak, ... Cell 166 (6), 1459-1470. e11, 2016 | 254 | 2016 |
| De novo protein design enables the precise induction of RSV-neutralizing antibodies F Sesterhenn, C Yang, J Bonet, JT Cramer, X Wen, Y Wang, CI Chiang, ... Science 368 (6492), eaay5051, 2020 | 153 | 2020 |
| Minimally mutated HIV-1 broadly neutralizing antibodies to guide reductionist vaccine design JG Jardine, D Sok, JP Julien, B Briney, A Sarkar, CH Liang, EA Scherer, ... PLoS pathogens 12 (8), e1005815, 2016 | 129 | 2016 |
| Bottom-up de novo design of functional proteins with complex structural features C Yang, F Sesterhenn, J Bonet, EA van Aalen, L Scheller, LA Abriata, ... Nature Chemical Biology, 1-9, 0 | 84 | |
| Rosetta FunFolDes–A general framework for the computational design of functional proteins J Bonet, S Wehrle, K Schriever, C Yang, A Billet, F Sesterhenn, A Scheck, ... PLoS computational biology 14 (11), e1006623, 2018 | 38 | 2018 |
| Boosting subdominant neutralizing antibody responses with a computationally designed epitope-focused immunogen F Sesterhenn, M Galloux, SS Vollers, L Csepregi, C Yang, D Descamps, ... PLoS biology 17 (2), e3000164, 2019 | 35 | 2019 |
| Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications L Malinovska, V Cappelletti, D Kohler, I Piazza, TH Tsai, M Pepelnjak, ... Nature Protocols 18 (3), 659-682, 2023 | 29 | 2023 |
| Structure-based immunogen design—leading the way to the new age of precision vaccines F Sesterhenn, J Bonet, BE Correia Current opinion in structural biology 51, 163-169, 2018 | 23 | 2018 |
| Global, in situ analysis of the structural proteome in individuals with Parkinson’s disease to identify a new class of biomarker MT Mackmull, L Nagel, F Sesterhenn, J Muntel, J Grossbach, P Stalder, ... Nature structural & molecular biology 29 (10), 978-989, 2022 | 18 | 2022 |
| rstoolbox-a Python library for large-scale analysis of computational protein design data and structural bioinformatics J Bonet, Z Harteveld, F Sesterhenn, A Scheck, BE Correia BMC bioinformatics 20, 1-13, 2019 | 13 | 2019 |
| A generic framework for hierarchical de novo protein design Z Harteveld, J Bonet, S Rosset, C Yang, F Sesterhenn, BE Correia Proceedings of the National Academy of Sciences 119 (43), e2206111119, 2022 | 10 | 2022 |
| The physiological landscape and specificity of antibody repertoires L Csepregi, KB Hoehn, D Neumeier, JM Taft, S Friedensohn, CR Weber, ... bioRxiv, 2021.09. 15.460420, 2021 | 5 | 2021 |
| Systematic identification of structure-specific protein–protein interactions A Holfeld, D Schuster, F Sesterhenn, P Stalder, W Haenseler, ... bioRxiv, 2023.02. 01.522707, 2023 | 3 | 2023 |
| Protein destabilization underlies pathogenic missense mutations in ARID1B F Mermet-Meillon, S Mercan, B Bauer-Probst, C Allard, M Bleu, K Calkins, ... Nature Structural & Molecular Biology, 1-5, 2024 | 2 | 2024 |
| mRNA Display Identifies Potent, Paralog-Selective Peptidic Ligands for ARID1B GS Cremosnik, Y Mesrouze, P Zueger, D Furkert, F Grandjean, D Argoti, ... ACS Chemical Biology, 2024 | | 2024 |
| Author Correction: Proteome-wide structural changes measured with limited proteolysis-mass spectrometry: an advanced protocol for high-throughput applications L Malinovska, V Cappelletti, D Kohler, I Piazza, TH Tsai, M Pepelnjak, ... Nature Protocols 18 (6), 1979-1979, 2023 | | 2023 |
| Immunogen B Correia, F Sesterhenn, C Yang, J Bonet US Patent App. 17/622,468, 2022 | | 2022 |
| Immunogen B Correia, F Sesterhenn, C Yang, J Bonet | | 2020 |
| Expanding beyond the natural protein repertoire to engineer targeted vaccines and diagnostics F Sesterhenn EPFL, 2019 | | 2019 |
