Postsynthetic modification of DNA phosphodiester backbone for photocaged DNAzyme X Wang, M Feng, L Xiao, A Tong, Y Xiang ACS chemical biology 11 (2), 444-451, 2016 | 67 | 2016 |
Orthogonal Activation of RNA‐Cleaving DNAzymes in Live Cells by Reactive Oxygen Species L Xiao, C Gu, Y Xiang Angewandte Chemie International Edition 58 (40), 14167-14172, 2019 | 62 | 2019 |
A simple design of fluorescent probes for indirect detection of β-lactamase based on AIE and ESIPT processes L Peng, L Xiao, Y Ding, Y Xiang, A Tong Journal of Materials Chemistry B 6 (23), 3922-3926, 2018 | 39 | 2018 |
Photocaged G-quadruplex DNAzyme and aptamer by post-synthetic modification on phosphodiester backbone M Feng, Z Ruan, J Shang, L Xiao, A Tong, Y Xiang Bioconjugate Chemistry 28 (2), 549-555, 2017 | 24 | 2017 |
Site-selective RNA functionalization via DNA-induced structure L Xiao, M Habibian, ET Kool Journal of the American Chemical Society 142 (38), 16357-16363, 2020 | 23 | 2020 |
DNA tiling enables precise acylation‐based labeling and control of mRNA L Xiao, YW Jun, ET Kool Angewandte Chemie International Edition 60 (51), 26798-26805, 2021 | 20 | 2021 |
Cationic peptide conjugation enhances the activity of peroxidase-mimicking DNAzymes L Xiao, Z Zhou, M Feng, A Tong, Y Xiang Bioconjugate Chemistry 27 (3), 621-627, 2016 | 20 | 2016 |
A general approach for rational design of fluorescent DNA aptazyme sensors based on target-induced unfolding of DNA hairpins Z Zhou, L Xiao, Y Xiang, J Zhou, A Tong Analytica Chimica Acta 889, 179-186, 2015 | 20 | 2015 |
Chemical synthesis of stimuli-responsive guide RNA for conditional control of CRISPR-Cas9 gene editing C Gu, L Xiao, J Shang, X Xu, L He, Y Xiang Chemical Science 12 (29), 9934-9945, 2021 | 17 | 2021 |
Pervasive transcriptome interactions of protein-targeted drugs L Fang, WA Velema, Y Lee, L Xiao, MG Mohsen, AM Kietrys, ET Kool Nature Chemistry 15 (10), 1374-1383, 2023 | 13 | 2023 |
Reversible 2′-OH acylation enhances RNA stability L Fang, L Xiao, YW Jun, Y Onishi, ET Kool Nature Chemistry 15 (9), 1296-1305, 2023 | 12 | 2023 |
Diverse reagent scaffolds provide differential selectivity of 2′-OH acylation in RNA L Xiao, L Fang, S Chatterjee, ET Kool Journal of the American Chemical Society 145 (1), 143-151, 2022 | 9 | 2022 |
Acylation probing of “generic” RNA libraries reveals critical influence of loop constraints on reactivity L Xiao, L Fang, ET Kool Cell chemical biology 29 (8), 1341-1352. e8, 2022 | 9 | 2022 |
Wavelength-selective activation of photocaged DNAzymes for metal ion sensing in live cells X Xu, L Xiao, C Gu, J Shang, Y Xiang ACS omega 6 (20), 13153-13160, 2021 | 8 | 2021 |
Quantification of total phosphorothioate in bacterial DNA by a bromoimane‐based fluorescent method L Xiao, Y Xiang Biotechnology Journal 11 (6), 824-830, 2016 | 8 | 2016 |
Efficient DNA fluorescence labeling via base excision trapping YW Jun, EM Harcourt, L Xiao, DL Wilson, ET Kool Nature Communications 13 (1), 5043, 2022 | 7 | 2022 |
Control of RNA with quinone methide reversible acylating reagents HS Park, B Jash, L Xiao, YW Jun, ET Kool Organic & biomolecular chemistry 19 (38), 8367-8376, 2021 | 6 | 2021 |
Reversible 2’-OH Acylation Enhances RNA Stability E Kool, L Fang, L Xiao, YW Jun, Y Onishi | 2 | 2022 |
Stereoselective RNA reaction with chiral 2′-OH acylating agents R Shioi, L Xiao, S Chatterjee, ET Kool Chemical Science 14 (45), 13235-13243, 2023 | 1 | 2023 |
Selective Arylation of RNA 2′‐OH Groups via SNAr Reaction with Trialkylammonium Heterocycles S Chatterjee, L Xiao, W Zhong, S Feng, ET Kool Angewandte Chemie, e202403496, 2024 | | 2024 |