|Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine|
KW Lee, NJ Kang, YS Heo, EA Rogozin, A Pugliese, MK Hwang, ...
Cancer research 68 (3), 946-955, 2008
|Polyphenols as small molecular inhibitors of signaling cascades in carcinogenesis|
NJ Kang, SH Shin, HJ Lee, KW Lee
Pharmacology & therapeutics 130 (3), 310-324, 2011
|Caffeic acid, a phenolic phytochemical in coffee, directly inhibits Fyn kinase activity and UVB-induced COX-2 expression|
NJ Kang, KW Lee, BJ Shin, SK Jung, MK Hwang, AM Bode, YS Heo, ...
Carcinogenesis 30 (2), 321-330, 2009
|Myricetin suppresses UVB-induced skin cancer by targeting Fyn|
SK Jung, KW Lee, S Byun, NJ Kang, SH Lim, YS Heo, AM Bode, ...
Cancer research 68 (14), 6021-6029, 2008
|Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1|
KW Lee, NJ Kang, EA Rogozin, HG Kim, YY Cho, AM Bode, HJ Lee, ...
Carcinogenesis 28 (9), 1918-1927, 2007
|Attenuation of oxidative neuronal cell death by coffee phenolic phytochemicals|
ES Cho, YJ Jang, MK Hwang, NJ Kang, KW Lee, HJ Lee
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 661 (1 …, 2009
|Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase|
JY Kwon, KW Lee, JE Kim, SK Jung, NJ Kang, MK Hwang, YS Heo, ...
Carcinogenesis 30 (11), 1932-1940, 2009
|Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-α-induced upregulation of matrix metalloproteinase-9: Its direct inhibition by quercetin|
MK Hwang, NR Song, NJ Kang, KW Lee, HJ Lee
The international journal of biochemistry & cell biology 41 (7), 1592-1600, 2009
|Coffee phenolic phytochemicals suppress colon cancer metastasis by targeting MEK and TOPK|
NJ Kang, KW Lee, BH Kim, AM Bode, HJ Lee, YS Heo, L Boardman, ...
Carcinogenesis 32 (6), 921-928, 2011
|Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf|
SK Jung, KW Lee, HY Kim, MH Oh, S Byun, SH Lim, YS Heo, NJ Kang, ...
Biochemical pharmacology 79 (10), 1455-1461, 2010
|Mitogen-and Stress-Activated Kinase 1–Mediated Histone H3 Phosphorylation Is Crucial for Cell Transformation|
HG Kim, KW Lee, YY Cho, NJ Kang, SM Oh, AM Bode, Z Dong
Cancer research 68 (7), 2538-2547, 2008
|Cocoa procyanidins suppress transformation by inhibiting mitogen-activated protein kinase kinase|
NJ Kang, KW Lee, DE Lee, EA Rogozin, AM Bode, HJ Lee, Z Dong
Journal of Biological Chemistry 283 (30), 20664-20673, 2008
|Phloretin induces apoptosis in H‐Ras MCF10A human breast tumor cells through the activation of p53 via JNK and p38 mitogen‐activated protein kinase signaling|
MS Kim, JY Kwon, NJ Kang, KW Lee, HJ Lee
Annals of the New York Academy of Sciences 1171 (1), 479, 2009
|Caffeic acid phenethyl ester inhibits invasion and expression of matrix metalloproteinase in SK-Hep1 human hepatocellular carcinoma cells by targeting nuclear factor kappa B|
KW Lee, NJ Kang, JH Kim, KM Lee, DE Lee, HJ Hur, HJ Lee
Genes & nutrition 2 (4), 319-322, 2008
|Enzymatic production of 3, 6-anhydro-L-galactose from agarose and its purification and in vitro skin whitening and anti-inflammatory activities|
EJ Yun, S Lee, JH Kim, BB Kim, HT Kim, SH Lee, JG Pelton, NJ Kang, ...
Applied microbiology and biotechnology 97 (7), 2961-2970, 2013
|Equol, a metabolite of the soybean isoflavone daidzein, inhibits neoplastic cell transformation by targeting the MEK/ERK/p90RSK/activator protein-1 pathway|
NJ Kang, KW Lee, EA Rogozin, YY Cho, YS Heo, AM Bode, HJ Lee, ...
Journal of Biological Chemistry 282 (45), 32856-32866, 2007
|Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis|
NJ Kang, SK Jung, KW Lee, HJ Lee
Annals of the new York Academy of sciences 1229 (1), 124-132, 2011
|7, 3′, 4′-Trihydroxyisoflavone, a metabolite of the soy isoflavone daidzein, suppresses ultraviolet B-induced skin cancer by targeting Cot and MKK4|
DE Lee, KW Lee, S Byun, SK Jung, N Song, SH Lim, YS Heo, JE Kim, ...
Journal of Biological Chemistry 286 (16), 14246-14256, 2011
|Cocoa polyphenols suppress TNF-α-induced vascular endothelial growth factor expression by inhibiting phosphoinositide 3-kinase (PI3K) and mitogen-activated protein kinase …|
JE Kim, JE Son, SK Jung, NJ Kang, CY Lee, KW Lee, HJ Lee
British journal of nutrition 104 (7), 957-964, 2010
|MKK4 is a novel target for the inhibition of tumor necrosis factor-α-induced vascular endothelial growth factor expression by myricetin|
JE Kim, JY Kwon, DE Lee, NJ Kang, YS Heo, KW Lee, HJ Lee
Biochemical pharmacology 77 (3), 412-421, 2009