Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy N Jumbe, A Louie, R Leary, W Liu, MR Deziel, VH Tam, R Bachhawat, ... The Journal of clinical investigation 112 (2), 275-285, 2003 | 336 | 2003 |
Pharmacokinetics of ranibizumab in patients with neovascular age-related macular degeneration: a population approach L Xu, T Lu, L Tuomi, N Jumbe, J Lu, S Eppler, P Kuebler, ... Investigative ophthalmology & visual science 54 (3), 1616-1624, 2013 | 220 | 2013 |
Pharmacodynamics of Daptomycin in a Murine Thigh Model of Staphylococcus aureus Infection A Louie, P Kaw, W Liu, N Jumbe, MH Miller, GL Drusano Antimicrobial agents and chemotherapy 45 (3), 845-851, 2001 | 198 | 2001 |
Passage of erythropoietic agents across the blood–brain barrier: a comparison of human and murine erythropoietin and the analog darbepoetin alfa WA Banks, NL Jumbe, CL Farrell, ML Niehoff, AC Heatherington European journal of pharmacology 505 (1-3), 93-101, 2004 | 173 | 2004 |
A comprehensive hepatitis C viral kinetic model explaining cure E Snoeck, P Chanu, M Lavielle, P Jacqmin, EN Jonsson, K Jorga, ... Clinical Pharmacology & Therapeutics 87 (6), 706-713, 2010 | 154 | 2010 |
Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice NL Jumbe, Y Xin, DD Leipold, L Crocker, D Dugger, E Mai, ... Journal of pharmacokinetics and pharmacodynamics 37, 221-242, 2010 | 131 | 2010 |
Quinolone Efflux Pumps Play a Central Role in Emergence of Fluoroquinolone Resistance in Streptococcus pneumoniae NL Jumbe, A Louie, MH Miller, W Liu, MR Deziel, VH Tam, R Bachhawat, ... Antimicrobial agents and chemotherapy 50 (1), 310-317, 2006 | 79 | 2006 |
Neuraminidase inhibitors for treatment of human and avian strain influenza: A comparative modeling study HM Dobrovolny, R Gieschke, BE Davies, NL Jumbe, CAA Beauchemin Journal of theoretical biology 269 (1), 234-244, 2011 | 56 | 2011 |
Use of quantitative pharmacology in the development of HAE1, a high-affinity anti-IgE monoclonal antibody WS Putnam, J Li, J Haggstrom, C Ng, S Kadkhodayan-Fischer, M Cheu, ... The AAPS journal 10, 425-430, 2008 | 51 | 2008 |
Levodopa prodrugs, and compositions and uses thereof JN Xiang, MA Gallop, CX Zhou, M Nguyen, X Dai, J Li, KC Cundy, ... US Patent 7,534,813, 2009 | 42 | 2009 |
Exploring cell tropism as a possible contributor to influenza infection severity HM Dobrovolny, MJ Baron, R Gieschke, BE Davies, NL Jumbe, ... PloS one 5 (11), e13811, 2010 | 41 | 2010 |
Onartuzumab (MetMAb): using nonclinical pharmacokinetic and concentration–effect data to support clinical development H Xiang, BC Bender, AE Reyes, M Merchant, NLS Jumbe, M Romero, ... Clinical Cancer Research 19 (18), 5068-5078, 2013 | 37 | 2013 |
Rituximab exhibits a long half-life based on a population pharmacokinetic analysis in non-Hodgkin’s lymphoma (NHL) patients. J Li, M Levi, JE Charoin, N Frey, T Kheoh, S Ren, M Woo, A Joshi, ... Blood, The Journal of the American Society of Hematology 110 (11), 2371-2371, 2007 | 33 | 2007 |
Population pharmacokinetic model of cabozantinib in patients with medullary thyroid carcinoma and its application to an exposure-response analysis D Miles, NL Jumbe, S Lacy, L Nguyen Clinical pharmacokinetics 55, 93-105, 2016 | 31 | 2016 |
Clinical trial simulation of a 200-microg fixed dose of darbepoetin alfa in chemotherapy-induced anemia. N Jumbe, B Yao, R Rovetti, G Rossi, AC Heatherington Oncology (Williston Park, NY) 16 (10 Suppl 11), 37-44, 2002 | 28 | 2002 |
Erythropoietic agents as neurotherapeutic agents: what barriers exist? NL Jumbe Oncology (Williston Park, NY) 16 (9 Suppl 10), 91-107, 2002 | 27 | 2002 |
Levodopa prodrugs, and compositions and uses thereof JN Xiang, MA Gallop, CX Zhou, M Nguyen, X Dai, J Li, KC Cundy, ... US Patent 7,342,131, 2008 | 26 | 2008 |
Levodopa prodrugs, and compositions and uses thereof JN Xiang, MA Gallop, CX Zhou, M Nguyen, X Dai, J Li, KC Cundy, ... US Patent 7,671,089, 2010 | 22 | 2010 |
Treatment method BC Bender, S Eppler, P Hegde, NL Jumbe, M Merchant, AC Peterson, ... US Patent App. 13/124,486, 2011 | 19 | 2011 |
Levodopa prodrugs, and compositions and uses thereof JN Xiang, MA Gallop, CX Zhou, M Nguyen, X Dai, J Li, KC Cundy, ... US Patent 7,956,212, 2011 | 15 | 2011 |