Immunity by formulation design: induction of high CD8+ T-cell responses by poly (I: C) incorporated into the CAF01 adjuvant via a double emulsion method P Nordly, F Rose, D Christensen, HM Nielsen, P Andersen, EM Agger, ... Journal of controlled release 150 (3), 307-317, 2011 | 105 | 2011 |
Engineering of a novel adjuvant based on lipid-polymer hybrid nanoparticles: A quality-by-design approach F Rose, JE Wern, PT Ingvarsson, M van de Weert, P Andersen, ... Journal of Controlled Release 210, 48-57, 2015 | 87 | 2015 |
A strong adjuvant based on glycol-chitosan-coated lipid-polymer hybrid nanoparticles potentiates mucosal immune responses against the recombinant Chlamydia trachomatis fusion … F Rose, JE Wern, F Gavins, P Andersen, F Follmann, C Foged Journal of Controlled Release 271, 88-97, 2018 | 53 | 2018 |
Identification of factors of importance for spray drying of small interfering RNA-loaded lipidoid-polymer hybrid nanoparticles for inhalation C Dormenval, A Lokras, G Cano-Garcia, A Wadhwa, K Thanki, F Rose, ... Pharmaceutical Research 36, 1-15, 2019 | 49 | 2019 |
Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: effect of charge, fluidity and antigen-to-lipid ratio M Hamborg, F Rose, L Jorgensen, K Bjorklund, HB Pedersen, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1838 (8), 2001-2010, 2014 | 44 | 2014 |
Immunological and physical evaluation of the multistage tuberculosis subunit vaccine candidate H56/CAF01 formulated as a spray-dried powder A Thakur, PT Ingvarsson, ST Schmidt, F Rose, P Andersen, D Christensen, ... Vaccine 36 (23), 3331-3339, 2018 | 35 | 2018 |
Dual-isotope SPECT/CT imaging of the tuberculosis subunit vaccine H56/CAF01: Induction of strong systemic and mucosal IgA and T-cell responses in mice upon subcutaneous prime … A Thakur, C Rodríguez-Rodríguez, K Saatchi, F Rose, T Esposito, ... Frontiers in immunology 9, 2825, 2018 | 26 | 2018 |
Formulation of RNA interference-based drugs for pulmonary delivery: challenges and opportunities K Thanki, KG Blum, A Thakur, F Rose, C Foged Therapeutic Delivery 9 (10), 731-749, 2018 | 23 | 2018 |
Mechanism of action of lung damage caused by a nanofilm spray product ST Larsen, C Dallot, SW Larsen, F Rose, SS Poulsen, AW Nørgaard, ... Toxicological Sciences 140 (2), 436-444, 2014 | 23 | 2014 |
The supramolecular structure is decisive for the immunostimulatory properties of synthetic analogues of a mycobacterial lipid in vitro B Martin-Bertelsen, KS Korsholm, F Rose, P Nordly, H Franzyk, ... RSC advances 3 (43), 20673-20683, 2013 | 22 | 2013 |
Influence of trehalose 6, 6′-diester (TDX) chain length on the physicochemical and immunopotentiating properties of DDA/TDX liposomes RS Kallerup, CM Madsen, ML Schiøth, H Franzyk, F Rose, D Christensen, ... European Journal of Pharmaceutics and Biopharmaceutics 90, 80-89, 2015 | 21 | 2015 |
Application of a quality-by-design approach to optimise lipid-polymer hybrid nanoparticles loaded with a splice-correction antisense oligonucleotide: maximising loading and … K Thanki, S Papai, A Lokras, F Rose, E Falkenberg, H Franzyk, C Foged Pharmaceutical research 36, 1-15, 2019 | 17 | 2019 |
Thinking machine: An'electronic clone'of a skilled engineer is very hard to create F Rose The Wall Street Journal 14, 1988 | 16 | 1988 |
Adjuvants based on synthetic mycobacterial cord factor analogues: biophysical properties of neat glycolipids and nanoself-assemblies with DDA RS Kallerup, H Franzyk, ML Schiøth, S Justesen, B Martin-Bertelsen, ... Molecular Pharmaceutics 14 (7), 2294-2306, 2017 | 9 | 2017 |
Design of gadoteridol-loaded cationic liposomal adjuvant CAF01 for MRI of lung deposition of intrapulmonary administered particles A Thakur, F Rose, SR Ansari, P Koch, V Martini, SL Ovesen, B Quistorff, ... Molecular Pharmaceutics 16 (11), 4725-4737, 2019 | 7 | 2019 |
Optimizing the design and dosing of dry powder inhaler formulations of the cationic liposome adjuvant CAF® 01 for pulmonary immunization A Thakur, Y Xu, G Cano-Garcia, S Feng, F Rose, P Gerde, P Andersen, ... Frontiers in Drug Delivery 2, 973599, 2022 | 6 | 2022 |
Temperature-induced self-assembly of the Group B Streptococcus (GBS) fusion antigen GBS-NN F Rose, S Roovers, M Fano, S Harloff-Helleberg, JJK Kirkensgaard, ... Molecular Pharmaceutics 15 (7), 2584-2593, 2018 | 6 | 2018 |
Dispersion of taste masked crystals or granules of active substances, chewable soft capsules filled with said dispersion, and process for preparing same J Meissonnier, F Rose, M Bohn US Patent App. 10/543,084, 2006 | 6 | 2006 |
Broadcom Puts Cable-Modem Circuitry On Single Chip, a Leap for the Industry F Rose The Wall Street Journal 139 (57), 0 | 5 | |
Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein–Based Fusion Antigen CTH522 Into Protein Nanoparticles F Rose, K Karlsen, PR Jensen, RU Jakobsen, GK Wood, KD Rand, ... Journal of Pharmaceutical Sciences 107 (6), 1690-1700, 2018 | 3 | 2018 |