Th17 cells promote autoimmune anti-myeloperoxidase glomerulonephritis PY Gan, OM Steinmetz, DSY Tan, KM O'Sullivan, JD Ooi, Y Iwakura, ... Journal of the American Society of Nephrology 21 (6), 925-931, 2010 | 208 | 2010 |
Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells JD Ooi, J Petersen, YH Tan, M Huynh, ZJ Willett, SH Ramarathinam, ... Nature 545 (7653), 243-247, 2017 | 205 | 2017 |
Cytokines: names and numbers you should care about SR Holdsworth, PY Gan Clinical journal of the American Society of Nephrology 10 (12), 2243-2254, 2015 | 190 | 2015 |
Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis KM O’Sullivan, CY Lo, SA Summers, KD Elgass, PJ McMillan, A Longano, ... Kidney international 88 (5), 1030-1046, 2015 | 159 | 2015 |
The Th17-defining transcription factor RORγt promotes glomerulonephritis OM Steinmetz, SA Summers, PY Gan, T Semple, SR Holdsworth, ... Journal of the American Society of Nephrology 22 (3), 472-483, 2011 | 118 | 2011 |
Innate IL-17A–producing leukocytes promote acute kidney injury via inflammasome and toll-like receptor activation AJ Chan, MA Alikhan, D Odobasic, PY Gan, MB Khouri, OM Steinmetz, ... The American journal of pathology 184 (5), 1411-1418, 2014 | 85 | 2014 |
Toll‐like receptor 2 induces Th17 myeloperoxidase autoimmunity while Toll‐like receptor 9 drives Th1 autoimmunity in murine vasculitis SA Summers, OM Steinmetz, PY Gan, JD Ooi, D Odobasic, AR Kitching, ... Arthritis & Rheumatism 63 (4), 1124-1135, 2011 | 82 | 2011 |
Mast cell activation and degranulation promotes renal fibrosis in experimental unilateral ureteric obstruction SA Summers, P Gan, L Dewage, FT Ma, JD Ooi, KM O'sullivan, ... Kidney international 82 (6), 676-685, 2012 | 79 | 2012 |
C5a receptor 1 promotes autoimmunity, neutrophil dysfunction and injury in experimental anti-myeloperoxidase glomerulonephritis J Dick, PY Gan, SL Ford, D Odobasic, MA Alikhan, SH Loosen, P Hall, ... Kidney International 93 (3), 615-625, 2018 | 68 | 2018 |
Interleukin-17A promotes early but attenuates established disease in crescentic glomerulonephritis in mice D Odobasic, PY Gan, SA Summers, TJ Semple, RCM Muljadi, Y Iwakura, ... The American journal of pathology 179 (3), 1188-1198, 2011 | 66 | 2011 |
Mast cells mediate acute kidney injury through the production of TNF SA Summers, J Chan, PY Gan, L Dewage, Y Nozaki, OM Steinmetz, ... Journal of the American Society of Nephrology 22 (12), 2226-2236, 2011 | 64 | 2011 |
Intrinsic renal cell and leukocyte-derived TLR4 aggravate experimental anti-MPO glomerulonephritis SA Summers, BS Van Der Veen, KM O'sullivan, PY Gan, JD Ooi, ... Kidney international 78 (12), 1263-1274, 2010 | 64 | 2010 |
Biologics for the treatment of autoimmune renal diseases SR Holdsworth, PY Gan, AR Kitching Nature Reviews Nephrology 12 (4), 217-231, 2016 | 61 | 2016 |
Mast cells contribute to peripheral tolerance and attenuate autoimmune vasculitis PY Gan, SA Summers, JD Ooi, KM O’Sullivan, DSY Tan, RCM Muljadi, ... Journal of the American Society of Nephrology 23 (12), 1955-1966, 2012 | 60 | 2012 |
Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN DSY Tan, PY Gan, KM O’Sullivan, MV Hammett, SA Summers, JD Ooi, ... Journal of the American Society of Nephrology 24 (4), 573-585, 2013 | 48 | 2013 |
A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity JD Ooi, JH Jiang, PJ Eggenhuizen, LL Chua, M van Timmeren, KL Loh, ... Nature communications 10 (1), 3392, 2019 | 47 | 2019 |
BCG vaccine derived peptides induce SARS-CoV-2 T cell cross-reactivity PJ Eggenhuizen, BH Ng, J Chang, AL Fell, RMY Cheong, WY Wong, ... Frontiers in immunology 12, 692729, 2021 | 43 | 2021 |
Myeloperoxidase (MPO)-specific CD4+ T cells contribute to MPO-anti-neutrophil cytoplasmic antibody (ANCA) associated glomerulonephritis PY Gan, SR Holdsworth, AR Kitching, JD Ooi Cellular Immunology 282 (1), 21-27, 2013 | 36 | 2013 |
Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis SA Summers, OM Steinmetz, JD Ooi, P Gan, KM O'Sullivan, ... The American journal of pathology 177 (5), 2234-2244, 2010 | 35 | 2010 |
Endogenous toll-like receptor 9 regulates AKI by promoting regulatory T cell recruitment MA Alikhan, SA Summers, PY Gan, AJ Chan, MB Khouri, JD Ooi, JR Ghali, ... Journal of the American Society of Nephrology 27 (3), 706-714, 2016 | 30 | 2016 |