Cigarette smoke and CFTR: implications in the pathogenesis of COPD A Rab, SM Rowe, SV Raju, Z Bebok, S Matalon, JF Collawn American Journal of Physiology-Lung Cellular and Molecular Physiology 305 (8 …, 2013 | 172 | 2013 |
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide … R Bartoszewski, JW Brewer, A Rab, DK Crossman, S Bartoszewska, ... Journal of Biological Chemistry 286 (48), 41862-41870, 2011 | 163 | 2011 |
The unfolded protein response (UPR)-activated transcription factor X-box-binding protein 1 (XBP1) induces microRNA-346 expression that targets the human antigen peptide … R Bartoszewski, JW Brewer, A Rab, DK Crossman, S Bartoszewska, ... Journal of Biological Chemistry 286 (48), 41862-41870, 2011 | 163 | 2011 |
Derivation of airway basal stem cells from human pluripotent stem cells FJ Hawkins, S Suzuki, ML Beermann, C Barillà, R Wang, ... Cell Stem Cell 28 (1), 79-95. e8, 2021 | 149 | 2021 |
Activation of the unfolded protein response by ΔF508 CFTR R Bartoszewski, A Rab, A Jurkuvenaite, M Mazur, J Wakefield, JF Collawn, ... American journal of respiratory cell and molecular biology 39 (4), 448-457, 2008 | 120 | 2008 |
The mechanism of cystic fibrosis transmembrane conductance regulator transcriptional repression during the unfolded protein response R Bartoszewski, A Rab, G Twitty, L Stevenson, J Fortenberry, A Piotrowski, ... Journal of biological chemistry 283 (18), 12154-12165, 2008 | 96 | 2008 |
Residual function of cystic fibrosis mutants predicts response to small molecule CFTR modulators ST Han, A Rab, MJ Pellicore, EF Davis, AF McCague, TA Evans, AT Joynt, ... JCI insight 3 (14), 2018 | 95 | 2018 |
Endoplasmic reticulum stress and the unfolded protein response regulate genomic cystic fibrosis transmembrane conductance regulator expression A Rab, R Bartoszewski, A Jurkuvenaite, J Wakefield, JF Collawn, Z Bebok American Journal of Physiology-Cell Physiology 292 (2), C756-C766, 2007 | 78 | 2007 |
A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion J Sharma, M Du, E Wong, V Mutyam, Y Li, J Chen, J Wangen, K Thrasher, ... Nature communications 12 (1), 4358, 2021 | 73 | 2021 |
The silent codon change I507-ATC→ ATT contributes to the severity of the ΔF508 CFTR channel dysfunction A Lazrak, L Fu, V Bali, R Bartoszewski, A Rab, V Havasi, S Keiles, ... The FASEB Journal 27 (11), 4630, 2013 | 73 | 2013 |
Restoration of W1282X CFTR activity by enhanced expression SM Rowe, K Varga, A Rab, Z Bebok, K Byram, Y Li, EJ Sorscher, ... American journal of respiratory cell and molecular biology 37 (3), 347-356, 2007 | 71 | 2007 |
CFTR expression regulation by the unfolded protein response R Bartoszewski, A Rab, L Fu, S Bartoszewska, J Collawn, Z Bebok Methods in enzymology 491, 3-24, 2011 | 59 | 2011 |
Highly efficient gene editing of cystic fibrosis patient-derived airway basal cells results in functional CFTR correction S Suzuki, AM Crane, V Anirudhan, C Barillà, N Matthias, SH Randell, ... Molecular Therapy 28 (7), 1684-1695, 2020 | 55 | 2020 |
Chymase mediates injury and mitochondrial damage in cardiomyocytes during acute ischemia/reperfusion in the dog J Zheng, CC Wei, N Hase, K Shi, CR Killingsworth, SH Litovsky, ... PLoS One 9 (4), e94732, 2014 | 54 | 2014 |
Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulator L Fu, A Rab, LP Tang, SM Rowe, Z Bebok, JF Collawn Biochemical Journal 441 (2), 633-643, 2012 | 50 | 2012 |
Hexose phosphorylation and the putative calcium channel component Mid1p are required for the hexose‐induced transient elevation of cytosolic calcium response in Saccharomyces … M Tökés‐Füzesi, DM Bedwell, I Repa, K Sipos, B Sümegi, A Rab, ... Molecular microbiology 44 (5), 1299-1308, 2002 | 50 | 2002 |
Robust stimulation of W1282X-CFTR channel activity by a combination of allosteric modulators W Wang, JS Hong, A Rab, EJ Sorscher, KL Kirk PLoS One 11 (3), e0152232, 2016 | 37 | 2016 |
Slowing ribosome velocity restores folding and function of mutant CFTR KE Oliver, R Rauscher, M Mijnders, W Wang, MJ Wolpert, J Maya, ... The Journal of clinical investigation 129 (12), 5236-5253, 2019 | 34 | 2019 |
VX-770-mediated potentiation of numerous human CFTR disease mutants is influenced by phosphorylation level G Cui, BB Stauffer, BR Imhoff, A Rab, JS Hong, EJ Sorscher, NA McCarty Scientific reports 9 (1), 13460, 2019 | 33 | 2019 |
ΔF508 CFTR surface stability is regulated by DAB2 and CHIP-mediated ubiquitination in post-endocytic compartments L Fu, A Rab, L Tang, Z Bebok, SM Rowe, R Bartoszewski, JF Collawn PLoS One 10 (4), e0123131, 2015 | 33 | 2015 |