| Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency MJ Ciancanelli, SXL Huang, P Luthra, H Garner, Y Itan, S Volpi, ... Science 348 (6233), 448-453, 2015 | 456 | 2015 |
| Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection S Aguirre, P Luthra, MT Sanchez-Aparicio, AM Maestre, J Patel, ... Nature microbiology 2 (5), 1-11, 2017 | 359 | 2017 |
| Function of the respiratory syncytial virus small hydrophobic protein S Fuentes, KC Tran, P Luthra, MN Teng, B He Journal of virology 81 (15), 8361-8366, 2007 | 262 | 2007 |
| Mutual antagonism between the Ebola virus VP35 protein and the RIG-I activator PACT determines infection outcome P Luthra, P Ramanan, CE Mire, C Weisend, Y Tsuda, B Yen, G Liu, ... Cell host & microbe 14 (1), 74-84, 2013 | 203 | 2013 |
| An intrinsically disordered peptide from Ebola virus VP35 controls viral RNA synthesis by modulating nucleoprotein-RNA interactions DW Leung, D Borek, P Luthra, JM Binning, M Anantpadma, G Liu, ... Cell reports 11 (3), 376-389, 2015 | 161 | 2015 |
| Severe influenza pneumonitis in children with inherited TLR3 deficiency HK Lim, SXL Huang, J Chen, G Kerner, O Gilliaux, P Bastard, K Dobbs, ... Journal of Experimental Medicine 216 (9), 2038-2056, 2019 | 155 | 2019 |
| Protein interaction mapping identifies RBBP6 as a negative regulator of Ebola virus replication J Batra, JF Hultquist, D Liu, O Shtanko, J Von Dollen, L Satkamp, ... Cell 175 (7), 1917-1930. e13, 2018 | 127 | 2018 |
| Activation of IFN-β expression by a viral mRNA through RNase L and MDA5 P Luthra, D Sun, RH Silverman, B He Proceedings of the National Academy of Sciences 108 (5), 2118-2123, 2011 | 109 | 2011 |
| The antiviral drug arbidol inhibits Zika virus SL Fink, L Vojtech, J Wagoner, NSJ Slivinski, KJ Jackson, R Wang, ... Scientific reports 8 (1), 8989, 2018 | 105 | 2018 |
| Development of RNA aptamers targeting Ebola virus VP35 JM Binning, T Wang, P Luthra, RS Shabman, DM Borek, G Liu, W Xu, ... Biochemistry 52 (47), 8406-8419, 2013 | 102 | 2013 |
| In silico derived small molecules bind the filovirus VP35 protein and inhibit its polymerase cofactor activity CS Brown, MS Lee, DW Leung, T Wang, W Xu, P Luthra, M Anantpadma, ... Journal of molecular biology 426 (10), 2045-2058, 2014 | 91 | 2014 |
| Cardiac inflammation in COVID-19: Lessons from heart failure SD Unudurthi, P Luthra, RJC Bose, JR McCarthy, MI Kontaridis Life sciences 260, 118482, 2020 | 88 | 2020 |
| Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses P Luthra, J Naidoo, CA Pietzsch, S De, S Khadka, M Anantpadma, ... Antiviral research 158, 288-302, 2018 | 86 | 2018 |
| The host E3-ubiquitin ligase TRIM6 ubiquitinates the Ebola virus VP35 protein and promotes virus replication P Bharaj, C Atkins, P Luthra, MI Giraldo, BE Dawes, L Miorin, JR Johnson, ... Journal of virology 91 (18), 10.1128/jvi. 00833-17, 2017 | 85 | 2017 |
| Differential regulation of interferon responses by Ebola and Marburg virus VP35 proteins MR Edwards, G Liu, CE Mire, S Sureshchandra, P Luthra, B Yen, ... Cell reports 14 (7), 1632-1640, 2016 | 80 | 2016 |
| Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing ebola virus immune evasion P Luthra, S Aguirre, BC Yen, CA Pietzsch, MT Sanchez-Aparicio, ... MBio 8 (2), 10.1128/mbio. 00368-17, 2017 | 72 | 2017 |
| Electron cryo-microscopy structure of Ebola virus nucleoprotein reveals a mechanism for nucleocapsid-like assembly Z Su, C Wu, L Shi, P Luthra, GD Pintilie, B Johnson, JR Porter, P Ge, ... Cell 172 (5), 966-978. e12, 2018 | 62 | 2018 |
| PLK1 down-regulates parainfluenza virus 5 gene expression D Sun, P Luthra, Z Li, B He PLoS pathogens 5 (7), e1000525, 2009 | 61 | 2009 |
| Ebola virus VP35 interaction with dynein LC8 regulates viral RNA synthesis P Luthra, DS Jordan, DW Leung, GK Amarasinghe, CF Basler Journal of virology 89 (9), 5148-5153, 2015 | 54 | 2015 |
| Ebola virus VP30 and nucleoprotein interactions modulate viral RNA synthesis W Xu, P Luthra, C Wu, J Batra, DW Leung, CF Basler, GK Amarasinghe Nature Communications 8 (1), 15576, 2017 | 53 | 2017 |
Christopher F. BaslerProfessor, Department of Microbiology, Icahn School of Medicine at Mount SinaiVerified email at mssm.edu
