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A Jeremy Willsey
A Jeremy Willsey
Associate Director of Data Science, Calico Life Sciences
calicolabs.com의 이메일 확인됨 - 홈페이지
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Synaptic, transcriptional and chromatin genes disrupted in autism
S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, ...
Nature 515 (7526), 209-215, 2014
27452014
The contribution of de novo coding mutations to autism spectrum disorder
I Iossifov, BJ O’roak, SJ Sanders, M Ronemus, N Krumm, D Levy, ...
Nature 515 (7526), 216-221, 2014
25562014
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
SJ Sanders, MT Murtha, AR Gupta, JD Murdoch, MJ Raubeson, ...
Nature 485 (7397), 237-241, 2012
23332012
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ...
Cell 180 (3), 568-584. e23, 2020
16992020
Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci
SJ Sanders, X He, AJ Willsey, AG Ercan-Sencicek, KE Samocha, ...
Neuron 87 (6), 1215-1233, 2015
14582015
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
10352019
Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder
MJ Gandal, P Zhang, E Hadjimichael, RL Walker, C Chen, S Liu, H Won, ...
Science 362 (6420), eaat8127, 2018
10062018
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism
AJ Willsey, SJ Sanders, M Li, S Dong, AT Tebbenkamp, RA Muhle, ...
Cell 155 (5), 997-1007, 2013
9432013
Comprehensive functional genomic resource and integrative model for the human brain
D Wang, S Liu, J Warrell, H Won, X Shi, FCP Navarro, D Clarke, M Gu, ...
Science 362 (6420), eaat8464, 2018
8052018
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ...
Nature genetics 45 (9), 984-994, 2013
7592013
Integrative functional genomic analysis of human brain development and neuropsychiatric risks
M Li, G Santpere, Y Imamura Kawasawa, OV Evgrafov, FO Gulden, ...
Science 362 (6420), eaat7615, 2018
6212018
Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
B Devlin, JR Kelsoe, P Sklar, MJ Daly, MC O'Donovan, N Craddock, ...
Nature neuroscience 18 (2), 199-209, 2015
5292015
Common genetic variants, acting additively, are a major source of risk for autism
L Klei, SJ Sanders, MT Murtha, V Hus, JK Lowe, AJ Willsey, ...
Molecular autism 3, 1-13, 2012
4672012
Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
DJ Weiner, EM Wigdor, S Ripke, RK Walters, JA Kosmicki, J Grove, ...
Nature genetics 49 (7), 978-985, 2017
4612017
The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment
J Cotney, RA Muhle, SJ Sanders, L Liu, AJ Willsey, W Niu, W Liu, L Klei, ...
Nature communications 6 (1), 6404, 2015
3432015
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24. 32 and a significant overlap with schizophrenia
Molecular autism 8, 1-17, 2017
3322017
The psychencode project
S Akbarian, C Liu, JA Knowles, FM Vaccarino, PJ Farnham, GE Crawford, ...
Nature neuroscience 18 (12), 1707-1712, 2015
3282015
Comparative flavivirus-host protein interaction mapping reveals mechanisms of dengue and Zika virus pathogenesis
PS Shah, N Link, GM Jang, PP Sharp, T Zhu, DL Swaney, JR Johnson, ...
Cell 175 (7), 1931-1945. e18, 2018
2752018
Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder
JY An, K Lin, L Zhu, DM Werling, S Dong, H Brand, HZ Wang, X Zhao, ...
Science 362 (6420), eaat6576, 2018
2692018
Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data
JT Glessner, AG Bick, K Ito, JG Homsy, L Rodriguez-Murillo, M Fromer, ...
Circulation research 115 (10), 884-896, 2014
2662014
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