| Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications J Zielonka, J Joseph, A Sikora, M Hardy, O Ouari, J Vasquez-Vivar, ... Chemical Reviews, 2017 | 1216 | 2017 |
| Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death G Cheng, J Zielonka, BP Dranka, D McAllister, AC Mackinnon, J Joseph, ... Cancer research 72 (10), 2634-2644, 2012 | 281 | 2012 |
| Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies B Kalyanaraman, G Cheng, M Hardy, O Ouari, B Bennett, J Zielonka Redox Biology, 2017 | 205 | 2017 |
| A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic … B Kalyanaraman, G Cheng, M Hardy, O Ouari, M Lopez, J Joseph, ... Redox Biology, 2017 | 205 | 2017 |
| Mitochondria-targeted analogs of metformin exhibit enhanced antiproliferative and radiosensitizing effects in pancreatic cancer cells G Cheng, J Zielonka, O Ouari, M Lopez, DM McAllister, KA Boyle, ... Cancer research, canres. 2534.2015, 2016 | 189 | 2016 |
| Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis G Cheng, Q Zhang, J Pan, Y Lee, O Ouari, M Hardy, M Zielonka, ... Nature Communications 10 (1), 2205, 2019 | 166 | 2019 |
| Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death G Cheng, J Zielonka, DM McAllister, AC Mackinnon, J Joseph, ... BMC cancer 13 (1), 285, 2013 | 142 | 2013 |
| Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling B Kalyanaraman, M Hardy, R Podsiadly, G Cheng, J Zielonka Archives of Biochemistry and Biophysics, 2016 | 126 | 2016 |
| Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation G Cheng, J Zielonka, D McAllister, S Tsai, MB Dwinell, B Kalyanaraman British journal of cancer 111 (1), 85-93, 2014 | 100 | 2014 |
| Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future G Cheng, M Zielonka, B Dranka, SN Kumar, CR Myers, B Bennett, ... Journal of Biological Chemistry, jbc. RA118. 003044, 2018 | 98 | 2018 |
| Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: role of mitochondrial bioenergetics and energy-sensing mechanism G Cheng, J Zielonka, D McAllister, M Hardy, O Ouari, J Joseph, ... Cancer Letters, 2015 | 83 | 2015 |
| High-throughput Assays for Superoxide and Hydrogen Peroxide DESIGN OF A SCREENING WORKFLOW TO IDENTIFY INHIBITORS OF NADPH OXIDASES J Zielonka, G Cheng, M Zielonka, T Ganesh, A Sun, J Joseph, R Michalski, ... Journal of Biological Chemistry 289 (23), 16176-16189, 2014 | 76 | 2014 |
| Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model JS Dickey, Y Gonzalez, B Aryal, S Mog, AJ Nakamura, CE Redon, U Baxa, ... PLOS ONE 8 (8), e70575, 2013 | 72 | 2013 |
| Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation J Zielonka, M Zielonka, L VerPlank, G Cheng, M Hardy, O Ouari, ... Journal of Biological Chemistry, jbc. M115. 702787, 2016 | 64 | 2016 |
| Beneficial effects of C36, a novel breaker of advanced glycation endproducts cross‐links, on the cardiovascular system of diabetic rats G Cheng, LL Wang, L Long, HY Liu, H Cui, WS Qu, S Li British journal of pharmacology 152 (8), 1196-1206, 2007 | 52 | 2007 |
| Mitochondria targeted honokiol confer a striking inhibitory effect on lung cancer via inhibiting complex I activity J Pan, Y Lee, G Cheng, J Zielonka, Q Zhang, M Bajzikova, D Xiong, ... iScience, 2018 | 45 | 2018 |
| C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats1 G Cheng, L WANG, W QU, L Long, H Cui, H LIU, Y CAO, S Li Acta Pharmacologica Sinica 26 (12), 1460-1466, 2005 | 42 | 2005 |
| Mitochondria-Targeted Antioxidant and Glycolysis Inhibition–Synergistic Therapy in Hepatocellular Carcinoma A Dhilip, G Cheng, J Joseph, S Kunnimalaiyaan, B Kalyanaraman, ... Anti-cancer drugs 24 (9), 881, 2013 | 40 | 2013 |
| Mitochondria-targeted nitroxides exacerbate fluvastatin-mediated cytostatic and cytotoxic effects in breast cancer cells G Cheng, M Lopez, J Zielonka, AD Hauser, J Joseph, D McAllister, ... Cancer biology & therapy 12 (8), 707-717, 2011 | 39 | 2011 |
| Potent inhibition of tumour cell proliferation and immunoregulatory function by mitochondria-targeted atovaquone G Cheng, M Hardy, P Topchyan, R Zander, P Volberding, W Cui, ... Scientific reports 10 (1), 1-14, 2020 | 37 | 2020 |
Jacek ZielonkaMedical College of WisconsinVerified email at mcw.edu
