Alejandro V. Villarino
Alejandro V. Villarino
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Posttranscriptional control of T cell effector function by aerobic glycolysis
CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ...
Cell 153 (6), 1239-1251, 2013
The JAK-STAT pathway: impact on human disease and therapeutic intervention
JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence
Annual review of medicine 66, 311-328, 2015
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system
JS Stumhofer, A Laurence, EH Wilson, E Huang, CM Tato, LM Johnson, ...
Nature immunology 7 (9), 937-945, 2006
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
AC Mullen, FA High, AS Hutchins, HW Lee, AV Villarino, DM Livingston, ...
Science 292 (5523), 1907-1910, 2001
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases
DM Schwartz, Y Kanno, A Villarino, M Ward, M Gadina, JJ O'Shea
Nature reviews Drug discovery 16 (12), 843-862, 2017
Mechanisms and consequences of Jak–STAT signaling in the immune system
AV Villarino, Y Kanno, JJ O'Shea
Nature immunology 18 (4), 374-384, 2017
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome
SW Canna, AA de Jesus, S Gouni, SR Brooks, B Marrero, Y Liu, ...
Nature genetics 46 (10), 1140-1146, 2014
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
A Villarino, L Hibbert, L Lieberman, E Wilson, T Mak, H Yoshida, ...
Immunity 19 (5), 645-655, 2003
Mechanisms of Jak/STAT signaling in immunity and disease
AV Villarino, Y Kanno, JR Ferdinand, JJ O’Shea
The Journal of Immunology 194 (1), 21-27, 2015
Non-classical immunity controls microbiota impact on skin immunity and tissue repair
JL Linehan, OJ Harrison, SJ Han, AL Byrd, I Vujkovic-Cvijin, AV Villarino, ...
Cell 172 (4), 784-796. e18, 2018
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
D Artis, A Villarino, M Silverman, W He, EM Thornton, S Mu, S Summer, ...
The Journal of Immunology 173 (9), 5626-5634, 2004
Understanding the pro-and anti-inflammatory properties of IL-27
AV Villarino, E Huang, CA Hunter
The Journal of Immunology 173 (2), 715-720, 2004
Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease
J Lohr, B Knoechel, JJ Wang, AV Villarino, AK Abbas
The Journal of experimental medicine 203 (13), 2785-2791, 2006
IL-27 limits IL-2 production during Th1 differentiation
AV Villarino, JS Stumhofer, CJM Saris, RA Kastelein, FJ de Sauvage, ...
The Journal of Immunology 176 (1), 237-247, 2006
T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire
Y Bronevetsky, AV Villarino, CJ Eisley, R Barbeau, AJ Barczak, GA Heinz, ...
Journal of Experimental Medicine 210 (2), 417-432, 2013
Positive and negative regulation of the IL-27 receptor during lymphoid cell activation
AV Villarino, J Larkin, CJM Saris, AJ Caton, S Lucas, T Wong, ...
The Journal of Immunology 174 (12), 7684-7691, 2005
Distinct requirements for T-bet in gut innate lymphoid cells
G Sciumè, K Hirahara, H Takahashi, A Laurence, AV Villarino, ...
Journal of Experimental Medicine 209 (13), 2331-2338, 2012
Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity
K Hirahara, A Onodera, AV Villarino, M Bonelli, G Sciumè, A Laurence, ...
Immunity 42 (5), 877-889, 2015
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
AV Villarino, CM Tato, JS Stumhofer, Z Yao, YK Cui, L Hennighausen, ...
The Journal of experimental medicine 204 (1), 65-71, 2007
STAT1-activating cytokines limit Th17 responses through both T-bet–dependent and–independent mechanisms
AV Villarino, E Gallo, AK Abbas
The Journal of Immunology 185 (11), 6461-6471, 2010
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