The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor H Yang, M Yang, Y Ding, Y Liu, Z Lou, Z Zhou, L Sun, L Mo, S Ye, H Pang, ... Proceedings of the National Academy of Sciences 100 (23), 13190-13195, 2003 | 1106 | 2003 |
The 3.8 Å resolution cryo-EM structure of Zika virus D Sirohi, Z Chen, L Sun, T Klose, TC Pierson, MG Rossmann, RJ Kuhn Science 352 (6284), 467-470, 2016 | 908 | 2016 |
RNA structure maps across mammalian cellular compartments L Sun, FM Fazal, P Li, JP Broughton, B Lee, L Tang, W Huang, ET Kool, ... Nature structural & molecular biology 26 (4), 322-330, 2019 | 201 | 2019 |
Crystal structure of methyl parathion hydrolase from Pseudomonas sp. WBC-3 YJ Dong, M Bartlam, L Sun, YF Zhou, ZP Zhang, CG Zhang, Z Rao, ... Journal of molecular biology 353 (3), 655-663, 2005 | 178 | 2005 |
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs L Sun, P Li, X Ju, J Rao, W Huang, L Ren, S Zhang, T Xiong, K Xu, X Zhou, ... Cell 184 (7), 1865-1883. e20, 2021 | 160 | 2021 |
Icosahedral bacteriophage ΦX174 forms a tail for DNA transport during infection L Sun, LN Young, X Zhang, SP Boudko, A Fokine, E Zbornik, ... Nature 505 (7483), 432-435, 2014 | 117 | 2014 |
Cryo-EM structure of the bacteriophage T4 portal protein assembly at near-atomic resolution L Sun, X Zhang, S Gao, PA Rao, V Padilla-Sanchez, Z Chen, S Sun, ... Nature communications 6 (1), 7548, 2015 | 112 | 2015 |
Integrative analysis of Zika virus genome RNA structure reveals critical determinants of viral infectivity P Li, Y Wei, M Mei, L Tang, L Sun, W Huang, J Zhou, C Zou, S Zhang, ... Cell host & microbe 24 (6), 875-886. e5, 2018 | 104 | 2018 |
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors Y Zhao, X Du, Y Duan, X Pan, Y Sun, T You, L Han, Z Jin, W Shang, J Yu, ... Protein & cell 12 (11), 877-888, 2021 | 102 | 2021 |
Refinement and analysis of the mature Zika virus cryo-EM structure at 3.1 Å resolution M Sevvana, F Long, AS Miller, T Klose, G Buda, L Sun, RJ Kuhn, ... Structure 26 (9), 1169-1177. e3, 2018 | 102 | 2018 |
Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody C Li, W Zhan, Z Yang, C Tu, G Hu, X Zhang, W Song, S Du, Y Zhu, ... Cell 185 (8), 1389-1401. e18, 2022 | 98 | 2022 |
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures L Sun, K Xu, W Huang, YT Yang, P Li, L Tang, T Xiong, QC Zhang Cell research 31 (5), 495-516, 2021 | 76 | 2021 |
Cryo-EM structure of the bacteriophage T4 isometric head at 3.3-Å resolution and its relevance to the assembly of icosahedral viruses Z Chen, L Sun, Z Zhang, A Fokine, V Padilla-Sanchez, D Hanein, W Jiang, ... Proceedings of the National Academy of Sciences 114 (39), E8184-E8193, 2017 | 70 | 2017 |
Structural basis for the function of DCN-1 in protein Neddylation X Yang, J Zhou, L Sun, Z Wei, J Gao, W Gong, RM Xu, Z Rao, Y Liu Journal of Biological Chemistry 282 (34), 24490-24494, 2007 | 68 | 2007 |
Comparison of viral RNA–host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2 S Zhang, W Huang, L Ren, X Ju, M Gong, J Rao, L Sun, P Li, Q Ding, ... Cell Research 32 (1), 9-23, 2022 | 56 | 2022 |
Crystal structure of the pyridoxal‐5′‐phosphate‐dependent serine dehydratase from human liver L Sun, M Bartlam, Y Liu, H Pang, Z Rao Protein science 14 (3), 791-798, 2005 | 44 | 2005 |
Advances and opportunities in RNA structure experimental determination and computational modeling J Zhang, Y Fei, L Sun, QC Zhang Nature methods 19 (10), 1193-1207, 2022 | 43 | 2022 |
Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain M Levisson, L Sun, S Hendriks, P Swinkels, T Akveld, JB Bultema, ... Journal of Molecular Biology 385 (3), 949-962, 2009 | 42 | 2009 |
Structure of the ribosome associating GTPase HflX H Wu, L Sun, F Blombach, SJJ Brouns, APL Snijders, K Lorenzen, ... Proteins: Structure, Function, and Bioinformatics 78 (3), 705-713, 2010 | 34 | 2010 |
Crystallization and preliminary X-ray studies of methyl parathion hydrolase from Pseudomonas sp. WBC-3 L Sun, Y Dong, Y Zhou, M Yang, C Zhang, Z Rao, X Zhang Acta Crystallographica Section D: Biological Crystallography 60 (5), 954-956, 2004 | 34 | 2004 |