| Distinct roles of GCN5/PCAF‐mediated H3K9ac and CBP/p300‐mediated H3K18/27ac in nuclear receptor transactivation Q Jin, LR Yu, L Wang, Z Zhang, LH Kasper, JE Lee, C Wang, PK Brindle, ... The EMBO journal 30 (2), 249-262, 2011 | 842 | 2011 |
| Replication fork stability confers chemoresistance in BRCA-deficient cells A Ray Chaudhuri, E Callen, X Ding, E Gogola, AA Duarte, JE Lee, ... Nature 535 (7612), 382-387, 2016 | 818 | 2016 |
| H3K4 mono-and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation JE Lee, C Wang, S Xu, YW Cho, L Wang, X Feng, A Baldridge, V Sartorelli, ... elife 2, e01503, 2013 | 470 | 2013 |
| Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis J Zhang, D Dominguez-Sola, S Hussein, JE Lee, AB Holmes, M Bansal, ... Nature medicine 21 (10), 1190-1198, 2015 | 451 | 2015 |
| The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ... Nature medicine 21 (10), 1199-1208, 2015 | 422 | 2015 |
| 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions E Callen, M Di Virgilio, MJ Kruhlak, M Nieto-Soler, N Wong, HT Chen, ... Cell 153 (6), 1266-1280, 2013 | 357 | 2013 |
| Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis L Wang, Q Jin, JE Lee, I Su, K Ge Proceedings of the National Academy of Sciences 107 (16), 7317-7322, 2010 | 310 | 2010 |
| Transcriptional and epigenetic regulation of PPARγ expression during adipogenesis JE Lee, K Ge Cell & bioscience 4, 1-11, 2014 | 235 | 2014 |
| UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity C Wang, JE Lee, YW Cho, Y Xiao, Q Jin, C Liu, K Ge Proceedings of the National Academy of Sciences 109 (38), 15324-15329, 2012 | 229 | 2012 |
| Transcriptional and epigenomic regulation of adipogenesis JE Lee, H Schmidt, B Lai, K Ge Molecular and cellular biology 39 (11), e00601-18, 2019 | 223 | 2019 |
| Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition C Wang, JE Lee, B Lai, TS Macfarlan, S Xu, L Zhuang, C Liu, W Peng, ... Proceedings of the National Academy of Sciences 113 (42), 11871-11876, 2016 | 216 | 2016 |
| Histone H3K9 methyltransferase G9a represses PPARγ expression and adipogenesis L Wang, S Xu, JE Lee, A Baldridge, S Grullon, W Peng, K Ge The EMBO journal 32 (1), 45-59, 2013 | 210 | 2013 |
| DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier MA Santos, RB Faryabi, AV Ergen, AM Day, A Malhowski, A Canela, ... Nature 514 (7520), 107-111, 2014 | 205 | 2014 |
| Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex H Kim, JE Lee, EJ Cho, JO Liu, HD Youn Cancer research 63 (19), 6135-6139, 2003 | 205 | 2003 |
| Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis JE Lee, YK Park, S Park, Y Jang, N Waring, A Dey, K Ozato, B Lai, ... Nature communications 8 (1), 2217, 2017 | 188 | 2017 |
| MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis B Lai, JE Lee, Y Jang, L Wang, W Peng, K Ge Nucleic acids research 45 (11), 6388-6403, 2017 | 153 | 2017 |
| Histone Methylation Regulator PTIP Is Required for PPARγ and C/EBPα Expression and Adipogenesis YW Cho, SH Hong, Q Jin, L Wang, JE Lee, O Gavrilova, K Ge Cell metabolism 10 (1), 27-39, 2009 | 148 | 2009 |
| KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation SY Ang, A Uebersohn, CI Spencer, Y Huang, JE Lee, K Ge, BG Bruneau Development 143 (5), 810-821, 2016 | 135 | 2016 |
| p53 regulates glucose metabolism by miR-34a HR Kim, JS Roe, JE Lee, EJ Cho, HD Youn Biochemical and biophysical research communications 437 (2), 225-231, 2013 | 120 | 2013 |
| Opposing functions of BRD4 isoforms in breast cancer SY Wu, CF Lee, HT Lai, CT Yu, JE Lee, H Zuo, SY Tsai, MJ Tsai, K Ge, ... Molecular cell 78 (6), 1114-1132. e10, 2020 | 107 | 2020 |
Kai Ge, PhDSenior Investigator and Section Chief, NIDDK, NIHVerified email at nih.gov
