| 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks SF Bunting, E Callén, N Wong, HT Chen, F Polato, A Gunn, A Bothmer, ... Cell 141 (2), 243-254, 2010 | 1799 | 2010 |
| Centrosome amplification and a defective G2–M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform–deficient cells X Xu, Z Weaver, SP Linke, C Li, J Gotay, XW Wang, CC Harris, T Ried, ... Molecular cell 3 (3), 389-395, 1999 | 1015 | 1999 |
| Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice RH Wang, K Sengupta, C Li, HS Kim, L Cao, C Xiao, S Kim, X Xu, ... Cancer cell 14 (4), 312-323, 2008 | 959 | 2008 |
| Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation X Xu, KU Wagner, D Larson, Z Weaver, C Li, T Ried, L Hennighausen, ... Nature genetics 22 (1), 37-43, 1999 | 923 | 1999 |
| A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression RH Wang, C Li, X Xu, Y Zheng, C Xiao, P Zerfas, S Cooperman, ... Cell metabolism 2 (6), 399-409, 2005 | 779 | 2005 |
| TGF-β/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage X Yang, L Chen, X Xu, C Li, C Huang, CX Deng The Journal of cell biology 153 (1), 35-46, 2001 | 779 | 2001 |
| Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction X Xu, M Weinstein, C Li, M Naski, RI Cohen, DM Ornitz, P Leder, C Deng Development 125 (4), 753-765, 1998 | 654 | 1998 |
| Silencing of unsynapsed meiotic chromosomes in the mouse JMA Turner, SK Mahadevaiah, O Fernandez-Capetillo, A Nussenzweig, ... Nature genetics 37 (1), 41-47, 2005 | 607 | 2005 |
| SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activity HS Kim, A Vassilopoulos, RH Wang, T Lahusen, Z Xiao, X Xu, C Li, ... Cancer cell 20 (4), 487-499, 2011 | 593 | 2011 |
| FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung M Weinstein, X Xu, K Ohyama, CX Deng Development 125 (18), 3615-3623, 1998 | 582 | 1998 |
| Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis HS Kim, C Xiao, RH Wang, T Lahusen, X Xu, A Vassilopoulos, ... Cell metabolism 12 (3), 224-236, 2010 | 525 | 2010 |
| Bmi1 regulates mitochondrial function and the DNA damage response pathway J Liu, L Cao, J Chen, S Song, IH Lee, C Quijano, H Liu, K Keyvanfar, ... Nature 459 (7245), 387-392, 2009 | 522 | 2009 |
| SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism SM Jeong, C Xiao, LWS Finley, T Lahusen, AL Souza, K Pierce, YH Li, ... Cancer cell 23 (4), 450-463, 2013 | 480 | 2013 |
| Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5 X Yang, LH Castilla, X Xu, C Li, J Gotay, M Weinstein, PP Liu, CX Deng Development 126 (8), 1571-1580, 1999 | 461 | 1999 |
| BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation JMA Turner, O Aprelikova, X Xu, R Wang, S Kim, GVR Chandramouli, ... Current Biology 14 (23), 2135-2142, 2004 | 443 | 2004 |
| The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice X Yang, C Li, X Xu, C Deng Proceedings of the National Academy of Sciences 95 (7), 3667-3672, 1998 | 437 | 1998 |
| Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis X Xu, W Qiao, SP Linke, L Cao, WM Li, PA Furth, CC Harris, CX Deng Nature genetics 28 (3), 266-271, 2001 | 424 | 2001 |
| A targeted disruption of the murine Brca1 gene causes γ-irradiation hypersensitivity and genetic instability SX Shen, Z Weaver, X Xu, C Li, M Weinstein, L Chen, XY Guan, T Ried, ... Oncogene 17 (24), 3115-3124, 1998 | 423 | 1998 |
| Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis RH Wang, Y Zheng, HS Kim, X Xu, L Cao, T Lahusen, MH Lee, C Xiao, ... Molecular cell 32 (1), 11-20, 2008 | 422 | 2008 |
| Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2 M Weinstein, X Yang, C Li, X Xu, J Gotay, CX Deng Proceedings of the National Academy of Sciences 95 (16), 9378-9383, 1998 | 396 | 1998 |
