Genotype–phenotype correlations in neonatal epilepsies caused by mutations in the voltage sensor of Kv7. 2 potassium channel subunits F Miceli, MV Soldovieri, P Ambrosino, V Barrese, M Migliore, MR Cilio, ... Proceedings of the National Academy of Sciences 110 (11), 4386-4391, 2013 | 198 | 2013 |
Early-onset epileptic encephalopathy caused by gain-of-function mutations in the voltage sensor of Kv7. 2 and Kv7. 3 potassium channel subunits F Miceli, MV Soldovieri, P Ambrosino, M De Maria, M Migliore, R Migliore, ... Journal of Neuroscience 35 (9), 3782-3793, 2015 | 181 | 2015 |
Activation and desensitization of trpv1 channels in sensory neurons by the peroxisome proliferator-activated receptor α agonist palmitoylethanolamide P Ambrosino, MV Soldovieri, C Russo, M Taglialatela British Journal of Pharmacology 168 (6), 1430-1444, 2013 | 146* | 2013 |
Novel KCNQ2 and KCNQ3 Mutations in a Large Cohort of Families with Benign Neonatal Epilepsy: First Evidence for an Altered Channel Regulation by Syntaxin‐1A MV Soldovieri, N Boutry‐Kryza, M Milh, D Doummar, B Heron, E Bourel, ... Human mutation 35 (3), 356-367, 2014 | 118 | 2014 |
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels LDC Mannelli, E Lucarini, L Micheli, I Mosca, P Ambrosino, MV Soldovieri, ... Neuropharmacology 121, 49-59, 2017 | 106 | 2017 |
The ever changing moods of calmodulin: how structural plasticity entails transductional adaptability A Villarroel, M Taglialatela, G Bernardo-Seisdedos, A Alaimo, J Agirre, ... Journal of molecular biology 426 (15), 2717-2735, 2014 | 102 | 2014 |
The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels FA Iannotti, C Silvestri, E Mazzarella, A Martella, D Calvigioni, F Piscitelli, ... Proceedings of the National Academy of Sciences 111 (24), E2472-E2481, 2014 | 95 | 2014 |
Infantile spasms and encephalopathy without preceding neonatal seizures caused by KCNQ2 R198Q, a gain‐of‐function variant JJ Millichap, F Miceli, M De Maria, C Keator, N Joshi, B Tran, ... Epilepsia 58 (1), e10-e15, 2017 | 94 | 2017 |
Expression and function of Kv7. 4 channels in rat cardiac mitochondria: possible targets for cardioprotection L Testai, V Barrese, MV Soldovieri, P Ambrosino, A Martelli, I Vinciguerra, ... Cardiovascular research 110 (1), 40-50, 2016 | 85 | 2016 |
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy F Rizzo, P Ambrosino, A Guacci, M Chetta, G Marchese, T Rocco, ... Molecular and Cellular Neuroscience 72, 54-63, 2016 | 84 | 2016 |
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction P Nappi, F Miceli, MV Soldovieri, P Ambrosino, V Barrese, M Taglialatela Pflügers Archiv-European Journal of Physiology 472, 881-898, 2020 | 76 | 2020 |
Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine V Barrese, F Miceli, MV Soldovieri, P Ambrosino, FA Iannotti, MR Cilio, ... Clinical pharmacology: advances and applications, 225-236, 2010 | 68 | 2010 |
Early treatment with quinidine in 2 patients with epilepsy of infancy with migrating focal seizures (EIMFS) due to gain-of-function KCNT1 mutations: functional studies … R Dilena, JC DiFrancesco, MV Soldovieri, A Giacobbe, P Ambrosino, ... Neurotherapeutics 15 (4), 1112-1126, 2018 | 55 | 2018 |
Epilepsy-causing mutations in Kv7. 2 C-terminus affect binding and functional modulation by calmodulin P Ambrosino, A Alaimo, S Bartollino, L Manocchio, M De Maria, I Mosca, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (9 …, 2015 | 55 | 2015 |
De novo gain‐of‐function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy P Ambrosino, MV Soldovieri, T Bast, PD Turnpenny, S Uhrig, S Biskup, ... Annals of neurology 83 (6), 1198-1204, 2018 | 51 | 2018 |
Neurounina-1, a novel compound that increases Na+/Ca2+ exchanger activity, effectively protects against stroke damage P Molinaro, M Cantile, O Cuomo, A Secondo, A Pannaccione, ... Molecular Pharmacology 83 (1), 142-156, 2013 | 51 | 2013 |
T-type channel blocking properties and antiabsence activity of two imidazo [1, 2-b] pyridazine derivatives structurally related to indomethacin MG Rimoli, E Russo, M Cataldi, R Citraro, P Ambrosino, D Melisi, ... Neuropharmacology 56 (3), 637-646, 2009 | 47 | 2009 |
Pharmacological targeting of neuronal Kv7. 2/3 channels: a focus on chemotypes and receptor sites F Miceli, MV Soldovieri, P Ambrosino, L Manocchio, I Mosca, ... Current medicinal chemistry 25 (23), 2637-2660, 2018 | 46 | 2018 |
Tryptamine-based derivatives as transient receptor potential melastatin type 8 (TRPM8) channel modulators A Bertamino, C Ostacolo, P Ambrosino, S Musella, V Di Sarno, T Ciaglia, ... Journal of Medicinal Chemistry 59 (5), 2179-2191, 2016 | 46 | 2016 |
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7. 2 potassium channels to phosphatidylinositol 4, 5-bisphosphate MV Soldovieri, P Ambrosino, I Mosca, M De Maria, E Moretto, F Miceli, ... Scientific reports 6 (1), 38167, 2016 | 45 | 2016 |