Chromosomal instability drives metastasis through a cytosolic DNA response SF Bakhoum, B Ngo, AM Laughney, JA Cavallo, CJ Murphy, P Ly, P Shah, ... Nature 553 (7689), 467-472, 2018 | 1194 | 2018 |
A benchmark for comparison of cell tracking algorithms M Maška, V Ulman, D Svoboda, P Matula, P Matula, C Ederra, A Urbiola, ... Bioinformatics 30 (11), 1609-1617, 2014 | 476 | 2014 |
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers CF Houlihan, N Vora, T Byrne, D Lewer, G Kelly, J Heaney, S Gandhi, ... The Lancet 396 (10246), e6-e7, 2020 | 247 | 2020 |
DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer N Kanu, MA Cerone, G Goh, LP Zalmas, J Bartkova, M Dietzen, ... Genome biology 17 (1), 1-15, 2016 | 171 | 2016 |
Perspective: APOBEC mutagenesis in drug resistance and immune escape in HIV and cancer evolution S Venkatesan, R Rosenthal, N Kanu, N McGranahan, J Bartek, ... Annals of Oncology 29 (3), 563-572, 2018 | 153 | 2018 |
Tumor evolutionary principles: how intratumor heterogeneity influences cancer treatment and outcome S Venkatesan, C Swanton American Society of Clinical Oncology Educational Book 36, e141-e149, 2016 | 113 | 2016 |
Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer EvolutionAPOBEC3 in Cancer Evolution S Venkatesan, M Angelova, C Puttick, H Zhai, DR Caswell, WT Lu, ... Cancer discovery 11 (10), 2456-2473, 2021 | 85 | 2021 |
Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution S Venkatesan, C Swanton, BS Taylor, JF Costello Cold Spring Harbor perspectives in medicine 7 (8), a026617, 2017 | 82 | 2017 |
DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells LMEB Pont, K Naipal, JJ Kloezeman, S Venkatesan, M van den Bent, ... Cancer letters 356 (2), 525-535, 2015 | 48 | 2015 |
The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells LMEB Pont, JKH Spoor, S Venkatesan, S Swagemakers, JJ Kloezeman, ... Genes & cancer 5 (11-12), 445, 2014 | 44 | 2014 |
Genetic biomarkers of drug response for small-molecule therapeutics targeting the RTK/Ras/PI3K, p53 or Rb pathway in glioblastoma S Venkatesan, MLM Lamfers, CMF Dirven, S Leenstra CNS oncology 5 (2), 77-90, 2016 | 34 | 2016 |
Constraints in cancer evolution S Venkatesan, NJ Birkbak, C Swanton Biochemical Society Transactions 45 (1), 1-13, 2017 | 29 | 2017 |
Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance MK Mayekar, DR Caswell, NI Vokes, EK Law, W Wu, W Hill, E Gronroos, ... bioRxiv, 2020 | 18 | 2020 |
The basal interstitial nucleus (BIN) of the cerebellum provides diffuse ascending inhibitory input to the floccular granule cell layer D Jaarsma, FGC Blot, B Wu, S Venkatesan, J Voogd, D Meijer, ... Journal of Comparative Neurology 526 (14), 2231-2256, 2018 | 18 | 2018 |
Evolutionary dynamics in pre-invasive neoplasia C Abbosh, S Venkatesan, SM Janes, RC Fitzgerald, C Swanton Current Opinion in Systems Biology 2, 1-8, 2017 | 11 | 2017 |
Overview of the patent expiry of (non-) tyrosine kinase inhibitors approved for clinical use in the EU and the US S Venkatesan, M Lamfers, S Leenstra, AG Vulto Generics and Biosimilars Initiative Journal 6 (2), 89-97, 2017 | 11 | 2017 |
TP53 mutated glioblastoma stem-like cell cultures are sensitive to dual mTORC1/2 inhibition while resistance in TP53 wild type cultures can be overcome by combined inhibition … S Venkatesan, M Hoogstraat, E Caljouw, T Pierson, JKH Spoor, ... Oncotarget 7 (36), 58435, 2016 | 10 | 2016 |
APOBEC3 as a driver of genetic intratumor heterogeneity S Venkatesan, M Angelova, J Bartkova, SF Bakhoum, J Bartek, N Kanu, ... Molecular & Cellular Oncology, 2014734, 2021 | | 2021 |
Research Article The Journal of Comparative Neurology Research in Systems Neuroscience D Jaarsma, FGC Blot, B Wu, S Venkatesan, J Voogd, D Meijer, ... | | 2018 |
Ibrutinib: Perspective for elderly with mantle cell lymphoma S Kwadijk-De Gijsel, S Venkatesan Pharmaceutisch Weekblad, 20-21, 2015 | | 2015 |