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David L. Lahr
David L. Lahr
Foghorn Therapeutics
Verified email at xoxy.net
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Year
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ...
Cell 171 (6), 1437-1452. e17, 2017
25322017
High-throughput phenotyping of lung cancer somatic mutations
AH Berger, AN Brooks, X Wu, Y Shrestha, C Chouinard, F Piccioni, ...
Cancer cell 30 (2), 214-228, 2016
2142016
Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
I Smith, PG Greenside, T Natoli, DL Lahr, D Wadden, I Tirosh, R Narayan, ...
PLoS biology 15 (11), e2003213, 2017
2032017
Fabrication and gas sensing performance of parallel assemblies of metal oxide nanotubes supported by porous aluminum oxide membranes
R Artzi-Gerlitz, KD Benkstein, DL Lahr, JL Hertz, CB Montgomery, ...
Sensors and Actuators B: Chemical 136 (1), 257-264, 2009
862009
A library of phosphoproteomic and chromatin signatures for characterizing cellular responses to drug perturbations
L Litichevskiy, R Peckner, JG Abelin, JK Asiedu, AL Creech, JF Davis, ...
Cell systems 6 (4), 424-443. e7, 2018
762018
Catalyzed CO oxidation at 70 K on an extended Au/Ni surface alloy
DL Lahr, ST Ceyer
Journal of the American Chemical Society 128 (6), 1800-1801, 2006
722006
The GCTx format and cmap {Py, R, M, J} packages: resources for optimized storage and integrated traversal of annotated dense matrices
OM Enache, DL Lahr, TE Natoli, L Litichevskiy, D Wadden, C Flynn, ...
Bioinformatics 35 (8), 1427-1429, 2019
602019
An overview of the challenges in designing, integrating, and delivering BARD: a public chemical-biology resource and query portal for multiple organizations, locations, and …
A de Souza, JA Bittker, DL Lahr, S Brudz, S Chatwin, TI Oprea, A Waller, ...
Journal of biomolecular screening 19 (5), 614-627, 2014
292014
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types
EA Howe, A de Souza, DL Lahr, S Chatwin, P Montgomery, BR Alexander, ...
Nucleic acids research 43 (D1), D1163-D1170, 2015
272015
Inducing analytical orthogonality in tungsten oxide-based microsensors using materials structure and dynamic temperature control
KD Benkstein, B Raman, DL Lahr, JE Bonevich, S Semancik
Sensors and Actuators B: Chemical 137 (1), 48-55, 2009
172009
Reactions of gas phase H atoms with ethylene, acetylene and ethane adsorbed on Ni (111)
T Bürgi, TR Trautman, M Gostein, DL Lahr, KL Haug, ST Ceyer
Surface science 501 (1-2), 49-73, 2002
172002
Origin of electrical signals for plasma etching end point detection: Comparison of end point signals and electron density
MA Sobolewski, DL Lahr
Journal of Vacuum Science & Technology A 30 (5), 2012
132012
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries
CA Mulrooney, DL Lahr, MJ Quintin, W Youngsaye, D Moccia, JK Asiedu, ...
Journal of computer-aided molecular design 27, 455-468, 2013
102013
A combinatorial study of thin-film process variables using microhotplates
DL Lahr, JL Hertz, S Semancik
Journal of Microelectromechanical Systems 19 (2), 239-245, 2010
72010
Preclinical validation of target engagement assays and investigation of mechanistic impacts of FHD-609, a clinical-stage BRD9 degrader being developed for the treatment of …
M Collins, J Wan, V Garbitt-Amaral, B Antonakos, HJ Wu, C Xu, DL Lahr, ...
strategies 36, 936-950, 2022
52022
Molecular oxygen adsorbates at a Au/Ni (111) surface alloy and their role in catalytic CO oxidation at 70-250 K
DL Lahr
Massachusetts Institute of Technology, 2006
32006
Abstract A049: Investigation of FHD-609, a potent degrader of BRD9, in preclinical models of acute myeloid leukemia (AML)
C Dominici, D Mayhew, A Adam, F Uzan, V Garbitt-Amaral, O Mikse, ...
Molecular Cancer Therapeutics 22 (12_Supplement), A049-A049, 2023
22023
Discovery of novel BAF inhibitors for the treatment of transcription factor-driven cancers
RC Centore, LM Soares, RG Vaswani, K Ichikawa, Z Li, H Fan, J Setser, ...
Cancer Research 81 (13_Supplement), 1224-1224, 2021
22021
Combinatorial Characterization of Chemiresistive Films Using Microhotplates
JL Hertz, DL Lahr, S Semancik
IEEE Sensors Journal 12 (5), 1459-1460, 2011
22011
Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
RC Centore, LMM Soares, S Topal, RG Vaswani, K Ichikawa, Z Li, H Fan, ...
bioRxiv, 2023.09. 11.557162, 2023
12023
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