| TMEM16 proteins produce volume-regulated chloride currents that are reduced in mice lacking TMEM16A J Almaça, Y Tian, F Aldehni, J Ousingsawat, P Kongsuphol, JR Rock, ... Journal of Biological Chemistry 284 (42), 28571-28578, 2009 | 213 | 2009 |
| Human beta cells produce and release serotonin to inhibit glucagon secretion from alpha cells J Almaça, J Molina, D Menegaz, AN Pronin, A Tamayo, V Slepak, ... Cell reports 17 (12), 3281-3291, 2016 | 206 | 2016 |
| SARS-CoV-2 cell entry factors ACE2 and TMPRSS2 are expressed in the microvasculature and ducts of human pancreas but are not enriched in β cells KC Coate, J Cha, S Shrestha, W Wang, LM Gonçalves, J Almaça, ... Cell metabolism 32 (6), 1028-1040. e4, 2020 | 173 | 2020 |
| The pericyte of the pancreatic islet regulates capillary diameter and local blood flow J Almaça, J Weitz, R Rodriguez-Diaz, E Pereira, A Caicedo Cell metabolism 27 (3), 630-644. e4, 2018 | 156 | 2018 |
| Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity JR Weitz, M Makhmutova, J Almaça, J Stertmann, K Aamodt, M Brissova, ... Diabetologia 61 (1), 182-192, 2018 | 97 | 2018 |
| ER-localized bestrophin 1 activates Ca2+-dependent ion channels TMEM16A and SK4 possibly by acting as a counterion channel R Barro-Soria, F Aldehni, J Almaça, R Witzgall, R Schreiber, ... Pflügers Archiv-European Journal of Physiology 459, 485-497, 2010 | 90 | 2010 |
| Young capillary vessels rejuvenate aged pancreatic islets J Almaça, J Molina, R Arrojo e Drigo, MH Abdulreda, WB Jeon, ... Proceedings of the National Academy of Sciences 111 (49), 17612-17617, 2014 | 87 | 2014 |
| β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions L Zhu, J Almaça, PK Dadi, H Hong, W Sakamoto, M Rossi, RJ Lee, ... Nature communications 8 (1), 14295, 2017 | 86 | 2017 |
| AMPK controls epithelial Na+ channels through Nedd4-2 and causes an epithelial phenotype when mutated J Almaça, P Kongsuphol, B Hieke, J Ousingsawat, B Viollet, R Schreiber, ... Pflügers Archiv-European Journal of Physiology 458, 713-721, 2009 | 72 | 2009 |
| Role of the Ca2+-activated Cl- channels bestrophin and anoctamin in epithelial cells K Kunzelmann, P Kongsuphol, K Chootip, C Toledo, JR Martins, J Almaca, ... Walter de Gruyter 392 (1-2), 125-134, 2011 | 68 | 2011 |
| Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell D Menegaz, DW Hagan, J Almaça, C Cianciaruso, R Rodriguez-Diaz, ... Nature metabolism 1 (11), 1110-1126, 2019 | 67 | 2019 |
| High-content siRNA screen reveals global ENaC regulators and potential cystic fibrosis therapy targets J Almaça, D Faria, M Sousa, I Uliyakina, C Conrad, L Sirianant, LA Clarke, ... Cell 154 (6), 1390-1400, 2013 | 64 | 2013 |
| Regulation of the epithelial Na+ channel by the protein kinase CK2 T Bachhuber, J Almaça, F Aldehni, A Mehta, MD Amaral, R Schreiber, ... Journal of biological chemistry 283 (19), 13225-13232, 2008 | 59 | 2008 |
| Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis JK Panzer, H Hiller, CM Cohrs, J Almaça, SJ Enos, M Beery, S Cechin, ... JCI insight 5 (8), 2020 | 58 | 2020 |
| Beta cell dysfunction in diabetes: the islet microenvironment as an unusual suspect J Almaça, A Caicedo, L Landsman Diabetologia 63 (10), 2076-2085, 2020 | 52 | 2020 |
| Pancreatic β-cells communicate with vagal sensory neurons M Makhmutova, J Weitz, A Tamayo, E Pereira, M Boulina, J Almaça, ... Gastroenterology 160 (3), 875-888. e11, 2021 | 50 | 2021 |
| Regulation of Cl− secretion by AMPK in vivo P Kongsuphol, B Hieke, J Ousingsawat, J Almaca, B Viollet, R Schreiber, ... Pflügers Archiv-European Journal of Physiology 457, 1071-1078, 2009 | 42 | 2009 |
| Long-term culture of human pancreatic slices as a model to study real-time islet regeneration MMF Qadir, S Álvarez-Cubela, J Weitz, JK Panzer, D Klein, ... Nature communications 11 (1), 3265, 2020 | 37 | 2020 |
| Spatial and temporal coordination of insulin granule exocytosis in intact human pancreatic islets J Almaça, T Liang, HY Gaisano, HG Nam, PO Berggren, A Caicedo Diabetologia 58, 2810-2818, 2015 | 34 | 2015 |
| Secretory functions of macrophages in the human pancreatic islet are regulated by endogenous purinergic signaling JR Weitz, C Jacques-Silva, MMF Qadir, O Umland, E Pereira, F Qureshi, ... Diabetes 69 (6), 1206-1218, 2020 | 32 | 2020 |
Alejandro CaicedoProfessor of MedicineVerified email at med.miami.edu
