| Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock A Kumar, D Roberts, KE Wood, B Light, JE Parrillo, S Sharma, R Suppes, ... Critical care medicine 34 (6), 1589-1596, 2006 | 7216 | 2006 |
| Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock A Kumar, P Ellis, Y Arabi, D Roberts, B Light, JE Parrillo, P Dodek, ... Chest 136 (5), 1237-1248, 2009 | 1354 | 2009 |
| Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: a propensity-matched analysis A Kumar, R Zarychanski, B Light, J Parrillo, D Maki, D Simon, D Laporta, ... Critical care medicine 38 (9), 1773-1785, 2010 | 544 | 2010 |
| DGIdb: mining the druggable genome M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ... Nature methods 10 (12), 1209-1210, 2013 | 508 | 2013 |
| Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization DE Arking, SL Pulit, L Crotti, P Van Der Harst, PB Munroe, TT Koopmann, ... Nature genetics 46 (8), 826-836, 2014 | 319 | 2014 |
| Deciphering a global network of functionally associated post‐translational modifications P Minguez, L Parca, F Diella, DR Mende, R Kumar, M Helmer‐Citterich, ... Molecular systems biology 8 (1), 599, 2012 | 272 | 2012 |
| Cross‐talk between phosphorylation and lysine acetylation in a genome‐reduced bacterium V van Noort, J Seebacher, S Bader, S Mohammed, I Vonkova, MJ Betts, ... Molecular systems biology 8 (1), 571, 2012 | 214 | 2012 |
| PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica WW Navarre, SB Zou, H Roy, JL Xie, A Savchenko, A Singer, ... Molecular cell 39 (2), 209-221, 2010 | 195 | 2010 |
| Timing of vasopressor initiation and mortality in septic shock: a cohort study V Beck, D Chateau, GL Bryson, A Pisipati, S Zanotti, JE Parrillo, A Kumar, ... Critical care 18, 1-8, 2014 | 178 | 2014 |
| Interaction between fluids and vasoactive agents on mortality in septic shock: a multicenter, observational study J Waechter, A Kumar, SE Lapinsky, J Marshall, P Dodek, Y Arabi, ... Critical care medicine 42 (10), 2158-2168, 2014 | 176 | 2014 |
| Antimicrobial therapeutic determinants of outcomes from septic shock among patients with cirrhosis YM Arabi, SI Dara, Z Memish, A Al Abdulkareem, HM Tamim, ... Hepatology 56 (6), 2305-2315, 2012 | 154 | 2012 |
| The prognostic effects of somatic mutations in ER-positive breast cancer OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ... Nature communications 9 (1), 3476, 2018 | 125 | 2018 |
| Mycobacterium tuberculosis septic shock S Kethireddy, RB Light, Y Mirzanejad, D Maki, Y Arabi, S Lapinsky, ... Chest 144 (2), 474-482, 2013 | 71 | 2013 |
| Unsupervised detection of cancer driver mutations with parsimony-guided learning RD Kumar, SJ Swamidass, R Bose Nature genetics 48 (10), 1288-1294, 2016 | 57 | 2016 |
| Statistically identifying tumor suppressors and oncogenes from pan-cancer genome-sequencing data RD Kumar, AC Searleman, SJ Swamidass, OL Griffith, R Bose Bioinformatics 31 (22), 3561-3568, 2015 | 57 | 2015 |
| Activated protein C and septic shock: a propensity-matched cohort study E Rimmer, A Kumar, S Doucette, J Marshall, S Dial, D Gurka, ... Critical care medicine 40 (11), 2974-2981, 2012 | 41 | 2012 |
| Prioritizing potentially druggable mutations with dGene: an annotation tool for cancer genome sequencing data RD Kumar, LW Chang, MJ Ellis, R Bose PloS one 8 (6), e67980, 2013 | 35 | 2013 |
| Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types RD Kumar, R Bose Scientific reports 7 (1), 6418, 2017 | 12 | 2017 |
| A deep intronic variant is a common cause of OTC deficiency in individuals with previously negative genetic testing RD Kumar, LC Burrage, J Bartos, S Ali, E Schmitt, SCS Nagamani, ... Molecular Genetics and Metabolism Reports 26, 100706, 2021 | 10 | 2021 |
| A TMPRSS2‐ERG gene signature predicts prognosis of patients with prostate adenocarcinoma E Zhou, B Zhang, K Zhu, E Schaafsma, RD Kumar, C Cheng Clinical and translational medicine 10 (8), 2020 | 10 | 2020 |
Dan ChateauAssistant Professor, Community Health Sciences, University of ManitobaVerified email at cpe.umanitoba.ca
