|Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation|
JV Lee, A Carrer, S Shah, NW Snyder, S Wei, S Venneti, AJ Worth, ...
Cell Metabolism 20 (2), 306-319, 2014
|EBF2 determines and maintains brown adipocyte identity|
S Rajakumari, J Wu, J Ishibashi, HW Lim, AH Giang, KJ Won, RR Reed, ...
Cell Metabolism 17 (4), 562-574, 2013
|Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice|
MJ Harms, J Ishibashi, W Wang, HW Lim, S Goyama, T Sato, M Kurokawa, ...
Cell Metabolism 19 (4), 593-604, 2014
|Dynamic chromatin remodeling mediated by polycomb proteins orchestrates pancreatic differentiation of human embryonic stem cells|
R Xie, LJ Everett, HW Lim, NA Patel, J Schug, E Kroon, OG Kelly, A Wang, ...
Cell Stem Cell 12 (2), 224-237, 2013
|Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor|
Z Sun, D Feng, B Fang, SE Mullican, SH You, HW Lim, LJ Everett, ...
Molecular Cell 52 (6), 769-782, 2013
|Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo|
SH You, HW Lim, Z Sun, M Broache, KJ Won, MA Lazar
Nature Structural & Molecular Biology 20 (2), 182-187, 2013
|Ebf2 is a selective marker of brown and beige adipogenic precursor cells|
W Wang, M Kissig, S Rajakumari, L Huang, H Lim, KJ Won, P Seale
Proceedings of the National Academy of Sciences 111 (40), 14466-14471, 2014
|Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue|
DA Hill, HW Lim, YH Kim, WY Ho, YH Foong, VL Nelson, HCB Nguyen, ...
Proceedings of the National Academy of Sciences 115 (22), E5096-E5105, 2018
|Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo|
HW Lim, NH Uhlenhaut, A Rauch, J Weiner, S Hübner, N Hübner, KJ Won, ...
Genome Research 25 (6), 836-844, 2015
|PRDM16 binds MED1 and controls chromatin architecture to determine a brown fat transcriptional program|
MJ Harms, HW Lim, Y Ho, SN Shapira, J Ishibashi, S Rajakumari, ...
Genes & Development 29 (3), 298-307, 2015
|Genetic variation determines PPARγ function and anti-diabetic drug response in vivo|
Cell 162 (1), 33–44, 2015
|Histone deacetylase 3 prepares brown adipose tissue for acute thermogenic challenge|
MJ Emmett, HW Lim, J Jager, HJ Richter, M Adlanmerini, LC Peed, ...
Nature 546 (7659), 544-548, 2017
|Anti-diabetic rosiglitazone remodels the adipocyte transcriptome by redistributing transcription to PPARγ-driven enhancers|
SE Step, HW Lim, JM Marinis, A Prokesch, DJ Steger, SH You, KJ Won, ...
Genes & Development 28 (9), 1018-1028, 2014
|EBF2 promotes the recruitment of beige adipocytes in white adipose tissue|
RR Stine, SN Shapira, HW Lim, J Ishibashi, M Harms, KJ Won, P Seale
Molecular Metabolism 5 (1), 57-65, 2016
|A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate|
W Wang, J Ishibashi, S Trefely, M Shao, AJ Cowan, A Sakers, HW Lim, ...
Cell Metabolism, 2019
|LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells|
BN Ediger, HW Lim, C Juliana, DN Groff, LQT Williams, G Dominguez, ...
Journal of Clinical Investigation 127 (1), 215-229, 2017
|Targeting ACLY sensitizes castration-resistant prostate cancer cells to AR antagonism by impinging on an ACLY-AMPK-AR feedback mechanism.|
S Shah, WJ Carriveau, J Li, SL Campbell, PK Kopinski, HW Lim, N Daurio, ...
Oncotarget 7 (28), 43713-43730, 2016
|EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex|
SN Shapira, HW Lim, S Rajakumari, AP Sakers, J Ishibashi, MJ Harms, ...
Genes & development 31 (7), 660-673, 2017
|Efficient initial pool generation for weighted graph problems using parallel overlap assembly|
JY Lee, HW Lim, SI Yoo, BT Zhang, TH Park
International Workshop on DNA-Based Computers, 215-223, 2004
|PRDM16 represses the type I interferon response in adipocytes to promote mitochondrial and thermogenic programing|
M Kissig, J Ishibashi, MJ Harms, HW Lim, RR Stine, KJ Won, P Seale
The EMBO journal 36 (11), 1528-1542, 2017