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Marc Kirschner
Marc Kirschner
Professor of Systems Biology, Harvard Medical School
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Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.
DW Cleveland, SG Fischer, MW Kirschner, UK Laemmli
Journal of Biological Chemistry 252 (3), 1102-1106, 1977
63541977
Dynamic instability of microtubule growth
T Mitchison, M Kirschner
nature 312 (5991), 237-242, 1984
41741984
A protein factor essential for microtubule assembly.
MD Weingarten, AH Lockwood, SY Hwo, MW Kirschner
Proceedings of the National Academy of Sciences 72 (5), 1858-1862, 1975
38611975
Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells
AM Klein, L Mazutis, I Akartuna, N Tallapragada, A Veres, V Li, L Peshkin, ...
Cell 161 (5), 1187-1201, 2015
33142015
Cyclin is degraded by the ubiquitin pathway
M Glotzer, AW Murray, MW Kirschner
Nature 349 (6305), 132-138, 1991
31171991
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS
SA Gerber, J Rush, O Stemman, MW Kirschner, SP Gygi
Proceedings of the National Academy of Sciences 100 (12), 6940-6945, 2003
22642003
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614-620, 2009
21672009
Number and evolutionary conservation of ¥á-and ¥â-tubulin and cytoplasmic ¥â-and ¥ã-actin genes using specific cloned cDNA probes
DW Cleveland, MA Lopata, RJ MacDonald, NJ Cowan, WJ Rutter, ...
Cell 20 (1), 95-105, 1980
20181980
A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage
J Newport, M Kirschner
Cell 30 (3), 675-686, 1982
19321982
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis
S Kothakota, T Azuma, C Reinhard, A Klippel, J Tang, K Chu, TJ McGarry, ...
Science 278 (5336), 294-298, 1997
17731997
How proteolysis drives the cell cycle
RW King, RJ Deshaies, JM Peters, MW Kirschner
Science 274 (5293), 1652-1659, 1996
17341996
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly
R Rohatgi, L Ma, H Miki, M Lopez, T Kirchhausen, T Takenawa, ...
Cell 97 (2), 221-231, 1999
17161999
Beyond self-assembly: from microtubules to morphogenesis
M Kirschner, T Mitchison
Cell 45 (3), 329-342, 1986
16911986
Evolvability
M Kirschner, J Gerhart
Proceedings of the National Academy of Sciences 95 (15), 8420-8427, 1998
16651998
Cyclin synthesis drives the early embryonic cell cycle
AW Murray, MW Kirschner
Nature 339 (6222), 275-280, 1989
15171989
Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation
M Jain, R Nilsson, S Sharma, N Madhusudhan, T Kitami, AL Souza, ...
Science 336 (6084), 1040-1044, 2012
14402012
Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos
E Amaya, TJ Musci, MW Kirschner
Cell 66 (2), 257-270, 1991
14031991
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity
AW Murray, MJ Solomon, MW Kirschner
Nature 339 (6222), 280-286, 1989
13881989
Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.
DN Drechsel, AA Hyman, MH Cobb, MW Kirschner
Molecular biology of the cell 3 (10), 1141-1154, 1992
12621992
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B
RW King, JM Peters, S Tugendreich, M Rolfe, P Hieter, MW Kirschner
Cell 81 (2), 279-288, 1995
12031995
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