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Padraig Mulcahy
Padraig Mulcahy
Unknown affiliation
Verified email at admin.cam.ac.uk
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Year
C9orf72 expansion disrupts ATM-mediated chromosomal break repair
C Walker, S Herranz-Martin, E Karyka, C Liao, K Lewis, W Elsayed, ...
Nature neuroscience 20 (9), 1225-1235, 2017
1712017
Further characterisation of the LPS model of Parkinson’s disease: a comparison of intra-nigral and intra-striatal lipopolysaccharide administration on motor function …
DB Hoban, E Connaughton, C Connaughton, G Hogan, C Thornton, ...
Brain, behavior, and immunity 27, 91-100, 2013
1222013
Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone
P Mulcahy, A O'doherty, A Paucard, T O'brien, D Kirik, E Dowd
Neuroscience 203, 170-179, 2012
662012
Characterisation of a novel model of Parkinson's disease by intra-striatal infusion of the pesticide rotenone
P Mulcahy, S Walsh, A Paucard, K Rea, E Dowd
Neuroscience 181, 234-242, 2011
562011
Viral delivery of C9orf72 hexanucleotide repeat expansions in mice leads to repeat-length-dependent neuropathology and behavioural deficits
S Herranz-Martin, J Chandran, K Lewis, P Mulcahy, A Higginbottom, ...
Disease models & mechanisms 10 (7), 859-868, 2017
502017
The behavioural and neuropathological impact of intranigral AAV-α-synuclein is exacerbated by systemic infusion of the Parkinson's disease-associated pesticide, rotenone, in rats
P Mulcahy, A O’Doherty, A Paucard, T O’Brien, D Kirik, E Dowd
Behavioural brain research 243, 6-15, 2013
352013
C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten
MJ Stopford, A Higginbottom, GM Hautbergue, J Cooper-Knock, ...
Human molecular genetics 26 (6), 1133-1145, 2017
322017
Gene therapy: a promising approach to treating spinal muscular atrophy
PJ Mulcahy, K Iremonger, E Karyka, S Herranz-Martin, KT Shum, ...
Human gene therapy 25 (7), 575-586, 2014
222014
Adeno-associated vectors for gene delivery to the nervous system
PJ Mulcahy, C Binny, B Muszynski, E Karyka, M Azzouz
Gene delivery and therapy for neurological disorders, 1-22, 2015
42015
A biomaterials approach to modulate striatal toxicity of gene vectors: A comparative study
B Newland, T Moloney, P Mulcahy, E Dowd, A Pandit
MOVEMENT DISORDERS 27, S148-S148, 2012
2012
Development and characterisation of a novel model of Parkinson's disease by sequential intra-nigral administration of AAV-alpha-synuclein and the pesticide, rotenone, in the rat
PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd
MOVEMENT DISORDERS 27, S491-S491, 2012
2012
Modelling Parkinson's disease by chronic systemic exposure of? alpha-synuclein overexpressing rats to the pesticide, rotenone
PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd
MOVEMENT DISORDERS 27, S491-S491, 2012
2012
Development of a dual-hit model of Parkinson's disease by
PJ Mulcahy
Neuroscience 181, 234-242, 2012
2012
Systemic Rotenone Does Not Enhance Parkinsonian Pathology Caused By Intracerebral Alpha-Synuclein In Rats
PJ Mulcahy, A O'Doherty, T O'Brien, D Kirik, E Dowd
Irish Journal of Medical Science 180, 20, 2011
2011
INTRACEREBRAL INFUSION OF ROTENONE INTO THE STRIATUM OR SUBSTANTIA NIGRA CAUSES BEHAVIOURAL DEFICITS AND NIGROSTRIATAL DEGENERATION ASSOCIATED WITH PARKINSON'S DISEASE
PJ Mulcahy, A Paucard, S Walsh, E Dowd
IRISH JOURNAL OF MEDICAL SCIENCE 179, S127-S128, 2010
2010
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Articles 1–15