Hallgeir Rui

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robert a. kirkenProfessor University of Texas at El PasoVerified email at utep.edu
Marja NevalainenProfessorVerified email at Jefferson.edu
Craig ShriverUniformed Services University of the Health SciencesVerified email at usuhs.edu
Richard PestellBaruch S Blumberg Institute, President Pennsylvania Cancer and Regenerative Medicine Research CenterVerified email at bblumberg.org
Terry HyslopProfessor, Division of Biostatistics, Thomas Jefferson UniversityVerified email at jefferson.edu
Inna ChervonevaProfessor of Biostatistics, Thomas Jefferson UniversityVerified email at jefferson.edu
Kay-Uwe WagnerProfessor, Karmanos Cancer Institute, Wayne State UniversityVerified email at wayne.edu
Michael P. Lisanti, MD-PhD, FRSA, FR...Professor and Chair of Translational Medicine, University of Salford (Greater Manchester)Verified email at salford.ac.uk
Adam ErtelAssistant Professor, Thomas Jefferson UniversityVerified email at jefferson.edu
Hai HuChief Scientific Officer, Chan Soon-Shiong Institute of Molecular Medicine at WindberVerified email at wriwindber.org
Chenguang WangLIPOGEN LLC.Verified email at lipogenes.com
Michael J FlisterDirector, ADC Discovery Research at Pfizer OncologyVerified email at pfizer.com
Carmen BergomWashington University in St. LouisVerified email at wustl.edu
Xuanmao JiaoPh.D., Associate Professor, Baruch S. Blumberg InstituteVerified email at bblumberg.org
Federica Sotgia, PhDProfessor & Chair, University of Salford (Greater Manchester), UKVerified email at salford.ac.uk
J. Alan DiehlChair, Department of Biochemistry, Case Western Reserve UniversityVerified email at case.edu
David RimmYale UniversityVerified email at yale.edu
Lawrence Andrew ShirleyAssistant Professor of Surgery, The Ohio State UniversityVerified email at osu.edu
Fan DongUniversity of ToledoVerified email at utoledo.edu
Peter McCueDirector of Pathology, Jefferson UniversityVerified email at jefferson.edu

Hallgeir Rui

Professor of Pharmacology, Physiology & Cancer Biology, Thomas Jefferson University

Verified email at jefferson.edu - Homepage

Breast Cancer


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Activation of receptor-associated tyrosine kinase JAK2 by prolactin. H Rui, RA Kirken, WL Farrar Journal of Biological Chemistry 269 (7), 5364-5368, 1994	419	1994
Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer D Li, Y Zhao, C Liu, X Chen, Y Qi, Y Jiang, C Zou, X Zhang, S Liu, X Wang, ... Clinical cancer research 17 (7), 1722-1730, 2011	358	2011
Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation PM Grimley, F Dong, H Rui Cytokine & growth factor reviews 10 (2), 131-157, 1999	299	1999
Signal transducer and activator of transcription-5 activation and breast cancer prognosis MT Nevalainen, J Xie, J Torhorst, L Bubendorf, P Haas, J Kononen, ... Journal of Clinical Oncology 22 (11), 2053-2060, 2004	269	2004
Inactivation of interferon receptor promotes the establishment of immune privileged tumor microenvironment KV Katlinski, J Gui, YV Katlinskaya, A Ortiz, R Chakraborty, ... Cancer cell 31 (2), 194-207, 2017	242	2017
Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells AS Sultan, J Xie, MJ LeBaron, EL Ealley, MT Nevalainen, H Rui Oncogene 24 (5), 746-760, 2005	233	2005
Prolactin recruits STAT1, STAT3 and STAT5 independent of conserved receptor tyrosines TYR402, TYR479, TYR515 and TYR580 L DaSilva, H Rui, RA Erwin, OMZ Howard, RA Kirken, MG Malabarba, ... Molecular and cellular endocrinology 117 (2), 131-140, 1996	220	1996
RB-pathway disruption in breast cancer: differential association with disease subtypes, disease-specific prognosis and therapeutic response A Ertel, JL Dean, H Rui, C Liu, A Witkiewicz, KE Knudsen, ES Knudsen Cell cycle 9 (20), 4153-4163, 2010	201	2010
Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice KU Wagner, A Krempler, AA Triplett, Y Qi, NM George, J Zhu, H Rui Molecular and cellular biology 24 (12), 5510-5520, 2004	196	2004
Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells H Yamashita, J Xu, RA Erwin, WL Farrar, RA Kirken, H Rui Journal of Biological Chemistry 273 (46), 30218-30224, 1998	187	1998
Growth signaling and JAK2 association mediated by membrane-proximal cytoplasmic regions of prolactin receptors L DaSilva, OM Howard, H Rui, RA Kirken, WL Farrar Journal of Biological Chemistry 269 (28), 18267-18270, 1994	185	1994
Jak2/Stat5 signaling in mammogenesis, breast cancer initiation and progression KU Wagner, H Rui Journal of mammary gland biology and neoplasia 13, 93-103, 2008	180	2008
Inhibition of transcription factor Stat5 induces cell death of human prostate cancer cells TJ Ahonen, J Xie, MJ LeBaron, J Zhu, M Nurmi, K Alanen, H Rui, ... Journal of Biological Chemistry 278 (29), 27287-27292, 2003	175	2003
JAK2 activation and cell proliferation induced by antibody-mediated prolactin receptor dimerization H Rui, JJ Lebrun, RA Kirken, PA Kelly, WL Farrar Endocrinology 135 (4), 1299-1306, 1994	174	1994
Prolactin receptor triggering. Evidence for rapid tyrosine kinase activation. H Rui, JY Djeu, GA Evans, PA Kelly, WL Farrar Journal of Biological Chemistry 267 (33), 24076-24081, 1992	165	1992
Stromal caveolin-1 levels predict early DCIS progression to invasive breast cancer AK Witkiewicz, A Dasgupta, K Nguyen, C Liu, AJ Kovatich, GF Schwartz, ... Cancer biology & therapy 8 (11), 1071-1079, 2009	161	2009
Effects of growth hormone and prolactin immune development and function WJ Murphy, H Rui, DL Longo Life sciences 57 (1), 1-14, 1995	148	1995
An interferon-driven oxysterol-based defense against tumor-derived extracellular vesicles A Ortiz, J Gui, F Zahedi, P Yu, C Cho, S Bhattacharya, CJ Carbone, Q Yu, ... Cancer cell 35 (1), 33-45. e6, 2019	144	2019
Prolactin activates Ras via signaling proteins SHC, growth factor receptor bound 2, and son of sevenless RA Erwin, RA Kirken, MG Malabarba, WL Farrar, H Rui Endocrinology 136 (8), 3512-3518, 1995	138	1995
CCR5 governs DNA damage repair and breast cancer stem cell expansion X Jiao, MA Velasco-Velazquez, M Wang, Z Li, H Rui, AR Peck, JE Korkola, ... Cancer research 78 (7), 1657-1671, 2018	136	2018

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