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Laurence Rahme
Laurence Rahme
Professor of Surgery, Microbiology and Immunobiology
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Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proceedings of the National Academy of Sciences 110 (9), 3507-3512, 2013
30532013
A network-based analysis of systemic inflammation in humans
SE Calvano, W Xiao, DR Richards, RM Felciano, HV Baker, RJ Cho, ...
Nature 437 (7061), 1032-1037, 2005
16532005
Common virulence factors for bacterial pathogenicity in plants and animals
LG Rahme, EJ Stevens, SF Wolfort, J Shao, RG Tompkins, FM Ausubel
Science 268 (5219), 1899-1902, 1995
15691995
Molecular mechanisms of bacterial virulence elucidated using a Pseudomonas aeruginosa–Caenorhabditis elegans pathogenesis model
S Mahajan-Miklos, MW Tan, LG Rahme, FM Ausubel
Cell 96 (1), 47-56, 1999
10121999
Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication
E Déziel, F Lépine, S Milot, J He, MN Mindrinos, RG Tompkins, ...
Proceedings of the National Academy of Sciences 101 (5), 1339-1344, 2004
7612004
Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors
MW Tan, LG Rahme, JA Sternberg, RG Tompkins, FM Ausubel
Proceedings of the National Academy of Sciences 96 (5), 2408-2413, 1999
7161999
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
DG Lee, JM Urbach, G Wu, NT Liberati, RL Feinbaum, S Miyata, ...
Genome biology 7, 1-14, 2006
7092006
Positive Correlation between Virulence ofPseudomonas aeruginosa Mutants in Mice and Insects
G Jander, LG Rahme, FM Ausubel
Journal of bacteriology 182 (13), 3843-3845, 2000
6622000
Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Genomic responses in mouse models poorly mimic human inflammatory diseases
J Seok, HS Warren, AG Cuenca, MN Mindrinos, HV Baker, W Xu, ...
Proc Natl Acad Sci USA 110 (9), 3507-3512, 2013
5462013
Plants and animals share functionally common bacterial virulence factors
LG Rahme, FM Ausubel, H Cao, E Drenkard, BC Goumnerov, GW Lau, ...
Proceedings of the National Academy of Sciences 97 (16), 8815-8821, 2000
5252000
Pseudomonas aeruginosa-Plant Root Interactions. Pathogenicity, Biofilm Formation, and Root Exudation
TS Walker, HP Bais, E Déziel, HP Schweizer, LG Rahme, R Fall, ...
Plant physiology 134 (1), 320-331, 2004
5212004
The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes
J He, RL Baldini, E Déziel, M Saucier, Q Zhang, NT Liberati, D Lee, ...
Proceedings of the National Academy of Sciences 101 (8), 2530-2535, 2004
5122004
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing‐regulated genes are modulated without affecting ¡¦
E Déziel, S Gopalan, AP Tampakaki, F Lépine, KE Padfield, M Saucier, ...
Molecular microbiology 55 (4), 998-1014, 2005
5032005
A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism
H Cao, G Krishnan, B Goumnerov, J Tsongalis, R Tompkins, LG Rahme
Proceedings of the National Academy of Sciences 98 (25), 14613-14618, 2001
4342001
Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors
LG Rahme, MW Tan, L Le, SM Wong, RG Tompkins, SB Calderwood, ...
Proceedings of the National Academy of Sciences 94 (24), 13245-13250, 1997
4211997
MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR‐class regulatory protein, has dual ligands
G Xiao, E Déziel, J He, F Lépine, B Lesic, MH Castonguay, S Milot, ...
Molecular microbiology 62 (6), 1689-1699, 2006
3532006
Drosophila melanogaster as a model for human intestinal infection and pathology
Y Apidianakis, LG Rahme
Disease models & mechanisms 4 (1), 21-30, 2011
3392011
Electrospray/mass spectrometric identification and analysis of 4-hydroxy-2-alkylquinolines (HAQs) produced by Pseudomonas aeruginosa
F Lépine, S Milot, E Déziel, J He, LG Rahme
Journal of the American Society for Mass Spectrometry 15, 862-869, 2004
3082004
Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity
M Starkey, F Lepine, D Maura, A Bandyopadhaya, B Lesic, J He, T Kitao, ...
PLoS pathogens 10 (8), e1004321, 2014
2772014
Plant and environmental sensory signals control the expression of hrp genes in Pseudomonas syringae pv. phaseolicola
LG Rahme, MN Mindrinos, NJ Panopoulos
Journal of bacteriology 174 (11), 3499-3507, 1992
2741992
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