Omar El-Agnaf
Omar El-Agnaf
Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation
Verified email at - Homepage
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Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
IG McKeith, BF Boeve, DW Dickson, G Halliday, JP Taylor, D Weintraub, ...
Neurology 89 (1), 88-100, 2017
Detection of oligomeric forms of α‐synuclein protein in human plasma as a potential biomarker for Parkinson's disease
OMA El‐Agnaf, SA Salem, KE Paleologou, MD Curran, MJ Gibson, ...
The FASEB journal 20 (3), 419-425, 2006
α‐Synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
OMA El-Agnaf, SA Salem, KE Paleologou, LJ Cooper, NJ Fullwood, ...
The FASEB Journal 17 (13), 1-16, 2003
Protein aggregation in the brain: the molecular basis for Alzheimer’s and Parkinson’s diseases
GB Irvine, OM El-Agnaf, GM Shankar, DM Walsh
Molecular medicine 14 (7), 451-464, 2008
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer
B Fauvet, MK Mbefo, MB Fares, C Desobry, S Michael, MT Ardah, E Tsika, ...
Journal of Biological Chemistry 287 (19), 15345-15364, 2012
Detection of elevated levels of α-synuclein oligomers in CSF from patients with Parkinson disease
T Tokuda, MM Qureshi, MT Ardah, S Varghese, SAS Shehab, T Kasai, ...
Neurology 75 (20), 1766-1770, 2010
Aggregates from mutant and wild-type α-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of β-sheet and amyloid-likeá…
OMA El-Agnaf, R Jakes, MD Curran, D Middleton, R Ingenito, E Bianchi, ...
FEBS letters 440 (1-2), 71-75, 1998
Decreased α-synuclein in cerebrospinal fluid of aged individuals and subjects with Parkinson’s disease
T Tokuda, SA Salem, D Allsop, T Mizuno, M Nakagawa, MM Qureshi, ...
Biochemical and biophysical research communications 349 (1), 162-166, 2006
Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
B Mollenhauer, V Cullen, I Kahn, B Krastins, TF Outeiro, I Pepivani, J Ng, ...
Experimental neurology 213 (2), 315-325, 2008
Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation
DM Walsh, M Townsend, MB Podlisny, GM Shankar, JV Fadeeva, ...
Journal of Neuroscience 25 (10), 2455-2462, 2005
Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of α-synuclein protein implicated in Parkinson's disease
OMA El-Agnaf, R Jakes, MD Curran, A Wallace
FEBS letters 440 (1-2), 67-70, 1998
Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease
BJ Tabner, S Turnbull, OMA El-Agnaf, D Allsop
Free Radical Biology and Medicine 32 (11), 1076-1083, 2002
Court JA, Schlossmacher MG, Allsop D. Detection of oligomeric forms of alpha-synuclein protein in human plasma as a potential biomarker for Parkinson’s disease
OM El-Agnaf, SA Salem, KE Paleologou, MD Curran, MJ Gibson
Faseb j 20 (3), 419-425, 2006
Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia
BJ Tabner, OMA El-Agnaf, S Turnbull, MJ German, KE Paleologou, ...
Journal of Biological Chemistry 280 (43), 35789-35792, 2005
CSF and blood biomarkers for Parkinson's disease
L Parnetti, L Gaetani, P Eusebi, S Paciotti, O Hansson, O El-Agnaf, ...
The Lancet Neurology 18 (6), 573-586, 2019
Oligomerization and toxicity of β-amyloid-42 implicated in Alzheimer's disease
OMA El-Agnaf, DS Mahil, BP Patel, BM Austen
Biochemical and biophysical research communications 273 (3), 1003-1007, 2000
α-Synuclein implicated in Parkinson’s disease catalyses the formation of hydrogen peroxide in vitro
S Turnbull, BJ Tabner, OMA El-Agnaf, S Moore, Y Davies, D Allsop
Free Radical Biology and Medicine 30 (10), 1163-1170, 2001
Detection of elevated levels of soluble α-synuclein oligomers in post-mortem brain extracts from patients with dementia with Lewy bodies
KE Paleologou, CL Kragh, DMA Mann, SA Salem, R Al-Shami, D Allsop, ...
Brain 132 (4), 1093-1101, 2009
Aggregation and neurotoxicity of α-synuclein and related peptides
OMA EI-Agnaf, GB Irvine
Biochemical Society Transactions 30 (4), 559-565, 2002
Cerebrospinal fluid biomarkers in Parkinson disease
L Parnetti, A Castrioto, D Chiasserini, E Persichetti, N Tambasco, ...
Nature Reviews Neurology 9 (3), 131-140, 2013
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