Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes Q Yang, TE Graham, N Mody, F Preitner, OD Peroni, JM Zabolotny, ... Nature 436 (7049), 356-362, 2005 | 2922 | 2005 |
The adipokine lipocalin 2 is regulated by obesity and promotes insulin resistance QW Yan, Q Yang, N Mody, TE Graham, CH Hsu, Z Xu, NE Houstis, ... Diabetes 56 (10), 2533-2540, 2007 | 537 | 2007 |
Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway N Mody, J Leitch, C Armstrong, J Dixon, P Cohen FEBS letters 502 (1-2), 21-24, 2001 | 318 | 2001 |
Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21 EK Lees, E Król, L Grant, K Shearer, C Wyse, E Moncur, AS Bykowska, ... Aging cell 13 (5), 817-827, 2014 | 201 | 2014 |
Improved glucose homeostasis in mice with muscle-specific deletion of protein-tyrosine phosphatase 1B M Delibegovic, KK Bence, N Mody, EG Hong, HJ Ko, JK Kim, BB Kahn, ... Molecular and cellular biology, 2007 | 196 | 2007 |
Long-term Fenretinide treatment prevents high-fat diet-induced obesity, insulin resistance, and hepatic steatosis F Preitner, N Mody, TE Graham, OD Peroni, BB Kahn American Journal of Physiology-Endocrinology and Metabolism 297 (6), E1420-E1429, 2009 | 122 | 2009 |
An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro N Mody, DG Campbell, N Morrice, M Peggie, P Cohen Biochemical Journal 372 (2), 567-575, 2003 | 122 | 2003 |
Decreased clearance of serum retinol-binding protein and elevated levels of transthyretin in insulin-resistant ob/ob mice N Mody, TE Graham, Y Tsuji, Q Yang, BB Kahn American Journal of Physiology-Endocrinology and Metabolism 294 (4), E785-E793, 2008 | 118 | 2008 |
Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity-and pharmacologically induced endoplasmic reticulum stress A Agouni, N Mody, C Owen, A Czopek, D Zimmer, M Bentires-Alj, ... Biochemical Journal 438 (2), 369-378, 2011 | 111 | 2011 |
Susceptibility to diet-induced obesity and glucose intolerance in the APP SWE/PSEN1 A246E mouse model of Alzheimer’s disease is associated … N Mody, A Agouni, GD McIlroy, B Platt, M Delibegovic Diabetologia 54, 2143-2151, 2011 | 97 | 2011 |
Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia … L Grant, KD Shearer, A Czopek, EK Lees, C Owen, A Agouni, J Workman, ... Diabetes 63 (2), 456-470, 2014 | 81 | 2014 |
Adipocyte-specific protein tyrosine phosphatase 1B deletion increases lipogenesis, adipocyte cell size and is a minor regulator of glucose homeostasis C Owen, A Czopek, A Agouni, L Grant, R Judson, EK Lees, GD Mcilroy, ... PloS one 7 (2), e32700, 2012 | 72 | 2012 |
Inducible liver-specific knockdown of protein tyrosine phosphatase 1B improves glucose and lipid homeostasis in adult mice C Owen, EK Lees, L Grant, DJ Zimmer, N Mody, KK Bence, M Delibegović Diabetologia 56, 2286-2296, 2013 | 70 | 2013 |
Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice EK Lees, R Banks, C Cook, S Hill, N Morrice, L Grant, N Mody, ... Scientific reports 7 (1), 9977, 2017 | 69 | 2017 |
Fenretinide treatment prevents diet-induced obesity in association with major alterations in retinoid homeostatic gene expression in adipose, liver, and hypothalamus GD Mcilroy, M Delibegovic, C Owen, PN Stoney, KD Shearer, ... Diabetes 62 (3), 825-836, 2013 | 68 | 2013 |
Neuronal human BACE1 knockin induces systemic diabetes in mice K Plucińska, R Dekeryte, D Koss, K Shearer, N Mody, PD Whitfield, ... Diabetologia 59, 1513-1523, 2016 | 64 | 2016 |
In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues A Agouni, C Owen, A Czopek, N Mody, M Delibegovic Biochemical and biophysical research communications 401 (1), 104-111, 2010 | 55 | 2010 |
The mechanisms of Fenretinide-mediated anti-cancer activity and prevention of obesity and type-2 diabetes N Mody, GD Mcilroy Biochemical pharmacology 91 (3), 277-286, 2014 | 54 | 2014 |
Deficiency in protein tyrosine phosphatase PTP1B shortens lifespan and leads to development of acute leukemia S Le Sommer, N Morrice, M Pesaresi, D Thompson, MA Vickers, ... Cancer research 78 (1), 75-87, 2018 | 46 | 2018 |
Methionine restriction improves renal insulin signalling in aged kidneys L Grant, EK Lees, LA Forney, N Mody, T Gettys, PAJ Brown, HM Wilson, ... Mechanisms of ageing and development 157, 35-43, 2016 | 43 | 2016 |