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Masuo Ohno
Masuo Ohno
Nathan Kline Institute and NYU Langone Medical Center
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Intraneuronal ¥â-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque ¡¦
H Oakley, SL Cole, S Logan, E Maus, P Shao, J Craft, ...
Journal of Neuroscience 26 (40), 10129-10140, 2006
32742006
BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease
M Ohno, EA Sametsky, LH Younkin, H Oakley, SG Younkin, M Citron, ...
Neuron 41 (1), 27-33, 2004
6772004
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1
RM Costa, NB Federov, JH Kogan, GG Murphy, J Stern, M Ohno, ...
nature 415 (6871), 526-530, 2002
6602002
¥á-CaMKII-dependent plasticity in the cortex is required for permanent memory
PW Frankland, C O'Brien, M Ohno, A Kirkwood, AJ Silva
Nature 411 (6835), 309-313, 2001
5172001
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ...
Brain 134 (1), 258-277, 2011
4842011
BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice
M Ohno, SL Cole, M Yasvoina, J Zhao, M Citron, R Berry, JF Disterhoft, ...
Neurobiology of disease 26 (1), 134-145, 2007
3612007
Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
R Kimura, M Ohno
Neurobiology of disease 33 (2), 229-235, 2009
3442009
Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1
M Ohno, L Chang, W Tseng, H Oakley, M Citron, WL Klein, R Vassar, ...
European Journal of Neuroscience 23 (1), 251-260, 2006
3232006
7, 8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease
L Devi, M Ohno
Neuropsychopharmacology 37 (2), 434-444, 2012
2932012
Mechanisms underlying insulin deficiency-induced acceleration of ¥â-amyloidosis in a mouse model of Alzheimer's disease
L Devi, MJ Alldred, SD Ginsberg, M Ohno
PloS one 7 (3), e32792, 2012
1732012
PERK mediates eIF2¥á phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease
L Devi, M Ohno
Neurobiology of aging 35 (10), 2272-2281, 2014
1662014
Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer¡¯s disease transgenic mice
R Kimura, L Devi, M Ohno
Journal of neurochemistry 113 (1), 248-261, 2010
1612010
Mitochondrial dysfunction and accumulation of the ¥â-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice
L Devi, M Ohno
Neurobiology of disease 45 (1), 417-424, 2012
1452012
Phospho-eIF2¥á level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice
L Devi, M Ohno
PloS one 5 (9), e12974, 2010
1452010
Sex-and brain region-specific acceleration of ¥â-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease
L Devi, MJ Alldred, SD Ginsberg, M Ohno
Molecular brain 3, 1-11, 2010
1422010
Roles of eIF2¥á kinases in the pathogenesis of Alzheimer¡¯s disease
M Ohno
Frontiers in molecular neuroscience 7, 22, 2014
1302014
Inducible, pharmacogenetic approaches to the study of learning and memory
M Ohno, PW Frankland, AP Chen, RM Costa, AJ Silva
Nature neuroscience 4 (12), 1238-1243, 2001
1162001
Increased neuronal excitability, synaptic plasticity, and learning in aged Kv¥â1. 1 knockout mice
GG Murphy, NB Fedorov, KP Giese, M Ohno, E Friedman, R Chen, ...
Current Biology 14 (21), 1907-1915, 2004
1142004
Blockade of hippocampal nicotinic receptors impairs working memory but not reference memory in rats
M Ohno, T Yamamoto, S Watanabe
Pharmacology Biochemistry and Behavior 45 (1), 89-93, 1993
1111993
Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis
DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ...
Autophagy 7 (7), 788-789, 2011
1092011
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