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Sachiko Hirosue
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Year
VEGF-C promotes immune tolerance in B16 melanomas and cross-presentation of tumor antigen by lymph node lymphatics
AW Lund, FV Duraes, S Hirosue, VR Raghavan, C Nembrini, SN Thomas, ...
Cell reports 1 (3), 191-199, 2012
3272012
Antigen delivery to dendritic cells by poly (propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation
S Hirosue, IC Kourtis, AJ van der Vlies, JA Hubbell, MA Swartz
Vaccine 28 (50), 7897-7906, 2010
2592010
Engineering approaches to immunotherapy
MA Swartz, S Hirosue, JA Hubbell
Science translational medicine 4 (148), 148rv9-148rv9, 2012
2412012
Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells
S Hirosue, E Vokali, VR Raghavan, M Rincon-Restrepo, AW Lund, ...
The Journal of Immunology 192 (11), 5002-5011, 2014
2052014
Antigens reversibly conjugated to a polymeric glyco-adjuvant induce protective humoral and cellular immunity
DS Wilson, S Hirosue, MM Raczy, L Bonilla-Ramirez, L Jeanbart, R Wang, ...
Nature materials 18 (2), 175-185, 2019
1942019
Primary human and rat β-cells release the intracellular autoantigens GAD65, IA-2, and proinsulin in exosomes together with cytokine-induced enhancers of immunity
C Cianciaruso, EA Phelps, M Pasquier, R Hamelin, D Demurtas, ...
Diabetes 66 (2), 460-473, 2017
1662017
Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses
DJ Dowling, EA Scott, A Scheid, I Bergelson, S Joshi, C Pietrasanta, ...
Journal of Allergy and Clinical Immunology 140 (5), 1339-1350, 2017
1482017
Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice
IC Kourtis, S Hirosue, A De Titta, S Kontos, T Stegmann, JA Hubbell, ...
PloS one 8 (4), e61646, 2013
1422013
Sub-100nm biodegradable polymer spheres capable of transporting and releasing nucleic acids
S Hirosue, BG Mueller, RS Langer, RC Mulligan
US Patent 6,254,890, 2001
1182001
Plasmid DNA encapsulation and release from solvent diffusion nanospheres
S Hirosue, BG Müller, RC Mulligan, R Langer
Journal of Controlled Release 70 (1-2), 231-242, 2001
992001
Modes of antigen presentation by lymph node stromal cells and their immunological implications
S Hirosue, J Dubrot
Frontiers in immunology 6, 151001, 2015
762015
Toward responsive architectures
P Beesley, S Hirosue, J Ruxton
Responsive Architectures: Subtle Technologies. Eds. Philip Beesley, Sachiko …, 2006
662006
Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses
M Rincon-Restrepo, A Mayer, S Hauert, DK Bonner, EA Phelps, ...
Biomaterials 132, 48-58, 2017
582017
Lymphatic endothelial cells prime naïve CD8+ T cells into memory cells under steady-state conditions
E Vokali, SS Yu, S Hirosue, M Rinçon-Restrepo, F V. Duraes, S Scherer, ...
Nature communications 11 (1), 538, 2020
572020
Synthetically glycosylated antigens induce antigen-specific tolerance and prevent the onset of diabetes
DS Wilson, M Damo, S Hirosue, MM Raczy, K Brünggel, G Diaceri, ...
Nature biomedical engineering 3 (10), 817-829, 2019
552019
Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction
S Hirosue, K Senn, N Clément, M Nonnenmacher, L Gigout, RM Linden, ...
Virology 367 (1), 10-18, 2007
512007
Polymer micelles with pyridyl disulfide-coupled antigen travel through lymphatics and show enhanced cellular responses following immunization
JK Eby, KY Dane, CP O’Neil, S Hirosue, MA Swartz, JA Hubbell
Acta biomaterialia 8 (9), 3210-3217, 2012
432012
Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein
C Galan-Navarro, M Rincon-Restrepo, G Zimmer, EO Saphire, JA Hubbell, ...
Virology 512, 161-171, 2017
292017
Polypropylene sulfide nanoparticle p24 vaccine promotes dendritic cell-mediated specific immune responses against HIV-1
SM Caucheteux, JP Mitchell, MO Ivory, S Hirosue, S Hakobyan, G Dolton, ...
Journal of Investigative Dermatology 136 (6), 1172-1181, 2016
242016
pH-Dependent lytic peptides discovered by phage display
S Hirosue, T Weber
Biochemistry 45 (20), 6476-6487, 2006
182006
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