Jia Guo
Jia Guo
Research Assistant Professor, George Mason University
Verified email at gmu.edu
Cited by
Cited by
The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
Z Li, J Guo, Y Wu, Q Zhou
Nucleic acids research 41 (1), 277-287, 2013
LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection
PJ Vorster, J Guo, A Yoder, W Wang, Y Zheng, X Xu, D Yu, M Spear, Y Wu
Journal of Biological Chemistry 286 (14), 12554-12564, 2011
Spinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells
J Guo, W Wang, D Yu, Y Wu
Journal of virology 85 (19), 9824-9833, 2011
Single-particle tracking of human immunodeficiency virus type 1 productive entry into human primary macrophages
Q Li, W Li, W Yin, J Guo, ZP Zhang, D Zeng, X Zhang, Y Wu, XE Zhang, ...
ACS nano 11 (4), 3890-3903, 2017
The trinity of the cortical actin in the initiation of HIV-1 infection
M Spear, J Guo, Y Wu
Retrovirology 9 (1), 1-13, 2012
Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors
Y Yin, K Zheng, N Eid, S Howard, JH Jeong, F Yi, J Guo, CM Park, ...
Journal of medicinal chemistry 58 (4), 1846-1861, 2015
Effects of microtubule modulators on HIV-1 infection of transformed and resting CD4 T cells
A Yoder, J Guo, D Yu, Z Cui, XE Zhang, Y Wu
Journal of virology 85 (6), 3020-3024, 2011
A dichotomy in cortical actin and chemotactic actin activity between human memory and naive T cells contributes to their differential susceptibility to HIV-1 infection
W Wang, J Guo, D Yu, PJ Vorster, WJ Chen, Y Wu
Journal of Biological Chemistry 287 (42), 35455-35469, 2012
Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells
S Iordanskiy, R Van Duyne, GC Sampey, CM Woodson, K Fry, ...
Virology 485, 1-15, 2015
HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration
M Spear, J Guo, A Turner, D Yu, W Wang, B Meltzer, S He, X Hu, H Shang, ...
Journal of Biological Chemistry 289 (10), 6949-6959, 2014
Genistein interferes with SDF-1-and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells
J Guo, X Xu, TK Rasheed, A Yoder, D Yu, H Liang, F Yi, T Hawley, T Jin, ...
Retrovirology 10 (1), 1-15, 2013
Discovery of novel small-molecule inhibitors of LIM domain kinase for inhibiting HIV-1
F Yi, J Guo, D Dabbagh, M Spear, S He, K Kehn-Hall, J Fontenot, Y Yin, ...
Journal of Virology 91 (13), e02418-16, 2017
Novel anti‐HIV therapeutics targeting chemokine receptors and actin regulatory pathways
M Spear, J Guo, Y Wu
Immunological reviews 256 (1), 300-312, 2013
Involvement of LIM kinase 1 in actin polarization in human CD4 T cells
X Xu, J Guo, PJ Vorster, Y Wu
Communicative & integrative biology 5 (4), 381-383, 2012
Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages
B Meltzer, D Dabbagh, J Guo, F Kashanchi, M Tyagi, Y Wu
Virology 518, 241-252, 2018
Inhibition of HIV replication in vitro by clinical immunosuppressants and chemotherapeutic agents
T Hawley, M Spear, J Guo, Y Wu
Cell & bioscience 3 (1), 1-6, 2013
Studies using IPS cells support a possible link between ZIKA and microcephaly
J Guo
Cell & bioscience 6 (1), 1-2, 2016
BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection
I Guendel, BW Meltzer, A Baer, SM Dever, K Valerie, J Guo, Y Wu, ...
Virology journal 12 (1), 1-14, 2015
HIV gp120 is an aberrant chemoattractant for blood resting CD4 T cells
J Guo, X Xu, W Yuan, T Jin, Y Wu
Current HIV research 10 (8), 636-642, 2012
Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody
S He, Y Fu, J Guo, M Spear, J Yang, B Trinité, C Qin, S Fu, Y Jiang, ...
Science advances 5 (1), eaat7911, 2019
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