|The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation|
Z Li, J Guo, Y Wu, Q Zhou
Nucleic acids research 41 (1), 277-287, 2013
|LIM kinase 1 modulates cortical actin and CXCR4 cycling and is activated by HIV-1 to initiate viral infection|
PJ Vorster, J Guo, A Yoder, W Wang, Y Zheng, X Xu, D Yu, M Spear, Y Wu
Journal of Biological Chemistry 286 (14), 12554-12564, 2011
|Spinoculation triggers dynamic actin and cofilin activity that facilitates HIV-1 infection of transformed and resting CD4 T cells|
J Guo, W Wang, D Yu, Y Wu
Journal of virology 85 (19), 9824-9833, 2011
|Single-particle tracking of human immunodeficiency virus type 1 productive entry into human primary macrophages|
Q Li, W Li, W Yin, J Guo, ZP Zhang, D Zeng, X Zhang, Y Wu, XE Zhang, ...
ACS nano 11 (4), 3890-3903, 2017
|The trinity of the cortical actin in the initiation of HIV-1 infection|
M Spear, J Guo, Y Wu
Retrovirology 9 (1), 1-13, 2012
|Bis-aryl urea derivatives as potent and selective LIM kinase (Limk) inhibitors|
Y Yin, K Zheng, N Eid, S Howard, JH Jeong, F Yi, J Guo, CM Park, ...
Journal of medicinal chemistry 58 (4), 1846-1861, 2015
|Effects of microtubule modulators on HIV-1 infection of transformed and resting CD4 T cells|
A Yoder, J Guo, D Yu, Z Cui, XE Zhang, Y Wu
Journal of virology 85 (6), 3020-3024, 2011
|A dichotomy in cortical actin and chemotactic actin activity between human memory and naive T cells contributes to their differential susceptibility to HIV-1 infection|
W Wang, J Guo, D Yu, PJ Vorster, WJ Chen, Y Wu
Journal of Biological Chemistry 287 (42), 35455-35469, 2012
|Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells|
S Iordanskiy, R Van Duyne, GC Sampey, CM Woodson, K Fry, ...
Virology 485, 1-15, 2015
|HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration|
M Spear, J Guo, A Turner, D Yu, W Wang, B Meltzer, S He, X Hu, H Shang, ...
Journal of Biological Chemistry 289 (10), 6949-6959, 2014
|Genistein interferes with SDF-1-and HIV-mediated actin dynamics and inhibits HIV infection of resting CD4 T cells|
J Guo, X Xu, TK Rasheed, A Yoder, D Yu, H Liang, F Yi, T Hawley, T Jin, ...
Retrovirology 10 (1), 1-15, 2013
|Discovery of novel small-molecule inhibitors of LIM domain kinase for inhibiting HIV-1|
F Yi, J Guo, D Dabbagh, M Spear, S He, K Kehn-Hall, J Fontenot, Y Yin, ...
Journal of Virology 91 (13), e02418-16, 2017
|Novel anti‐HIV therapeutics targeting chemokine receptors and actin regulatory pathways|
M Spear, J Guo, Y Wu
Immunological reviews 256 (1), 300-312, 2013
|Involvement of LIM kinase 1 in actin polarization in human CD4 T cells|
X Xu, J Guo, PJ Vorster, Y Wu
Communicative & integrative biology 5 (4), 381-383, 2012
|Tat controls transcriptional persistence of unintegrated HIV genome in primary human macrophages|
B Meltzer, D Dabbagh, J Guo, F Kashanchi, M Tyagi, Y Wu
Virology 518, 241-252, 2018
|Inhibition of HIV replication in vitro by clinical immunosuppressants and chemotherapeutic agents|
T Hawley, M Spear, J Guo, Y Wu
Cell & bioscience 3 (1), 1-6, 2013
|Studies using IPS cells support a possible link between ZIKA and microcephaly|
Cell & bioscience 6 (1), 1-2, 2016
|BRCA1 functions as a novel transcriptional cofactor in HIV-1 infection|
I Guendel, BW Meltzer, A Baer, SM Dever, K Valerie, J Guo, Y Wu, ...
Virology journal 12 (1), 1-14, 2015
|HIV gp120 is an aberrant chemoattractant for blood resting CD4 T cells|
J Guo, X Xu, W Yuan, T Jin, Y Wu
Current HIV research 10 (8), 636-642, 2012
|Cofilin hyperactivation in HIV infection and targeting the cofilin pathway using an anti-α4β7 integrin antibody|
S He, Y Fu, J Guo, M Spear, J Yang, B Trinité, C Qin, S Fu, Y Jiang, ...
Science advances 5 (1), eaat7911, 2019