Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions SI Hung, WH Chung, SH Jee, WC Chen, YT Chang, WR Lee, SL Hu, ... Pharmacogenetics and genomics 16 (4), 297-306, 2006 | 822 | 2006 |
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection C Yao, HW Sun, NE Lacey, Y Ji, EA Moseman, HY Shih, EF Heuston, ... Nature immunology 20 (7), 890-901, 2019 | 431 | 2019 |
Developmental acquisition of regulomes underlies innate lymphoid cell functionality HY Shih, G Sciumè, Y Mikami, L Guo, HW Sun, SR Brooks, JF Urban, ... Cell 165 (5), 1120-1133, 2016 | 309 | 2016 |
Shared and restricted T-cell receptor use is crucial for carbamazepine-induced Stevens-Johnson syndrome TM Ko, WH Chung, CY Wei, HY Shih, JK Chen, CH Lin, YT Chen, SI Hung Journal of Allergy and Clinical Immunology 128 (6), 1266-1276. e11, 2011 | 301 | 2011 |
Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury OJ Harrison, JL Linehan, HY Shih, N Bouladoux, SJ Han, M Smelkinson, ... Science 363 (6422), eaat6280, 2019 | 273 | 2019 |
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers R Roychoudhuri, D Clever, P Li, Y Wakabayashi, KM Quinn, CA Klebanoff, ... Nature immunology 17 (7), 851-860, 2016 | 262 | 2016 |
Neuropeptide CGRP limits group 2 innate lymphoid cell responses and constrains type 2 inflammation H Nagashima, T Mahlakõiv, HY Shih, FP Davis, F Meylan, Y Huang, ... Immunity 51 (4), 682-695. e6, 2019 | 211 | 2019 |
Homeostatic control of sebaceous glands by innate lymphoid cells regulates commensal bacteria equilibrium T Kobayashi, B Voisin, EA Kennedy, JH Jo, HY Shih, A Truong, T Doebel, ... Cell 176 (5), 982-997. e16, 2019 | 182 | 2019 |
Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity K Hirahara, A Onodera, AV Villarino, M Bonelli, G Sciumè, A Laurence, ... Immunity 42 (5), 877-889, 2015 | 157 | 2015 |
Neuronal enhancers are hotspots for DNA single-strand break repair W Wu, SE Hill, WJ Nathan, J Paiano, E Callen, D Wang, K Shinoda, ... Nature 593 (7859), 440-444, 2021 | 140 | 2021 |
IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection A Boudil, IR Matei, HY Shih, G Bogdanoski, JS Yuan, SG Chang, ... Nature immunology 16 (4), 397-405, 2015 | 124 | 2015 |
Prenatal maternal infection promotes tissue-specific immunity and inflammation in offspring AI Lim, T McFadden, VM Link, SJ Han, RM Karlsson, A Stacy, TK Farley, ... Science 373 (6558), eabf3002, 2021 | 119 | 2021 |
Mucus sialylation determines intestinal host-commensal homeostasis Y Yao, G Kim, S Shafer, Z Chen, S Kubo, Y Ji, J Luo, W Yang, SP Perner, ... Cell 185 (7), 1172-1188. e28, 2022 | 97 | 2022 |
Tcra gene recombination is supported by a Tcra enhancer-and CTCF-dependent chromatin hub HY Shih, J Verma-Gaur, A Torkamani, AJ Feeney, N Galjart, MS Krangel Proceedings of the National Academy of Sciences 109 (50), E3493-E3502, 2012 | 95 | 2012 |
Human retinoic acid–regulated CD161+ regulatory T cells support wound repair in intestinal mucosa GAM Povoleri, E Nova-Lamperti, C Scottà, G Fanelli, YC Chen, PD Becker, ... Nature immunology 19 (12), 1403-1414, 2018 | 92 | 2018 |
Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions A Villarino, A Laurence, GW Robinson, M Bonelli, B Dema, B Afzali, ... Elife 5, e08384, 2016 | 90 | 2016 |
Transcriptional and epigenetic networks of helper T and innate lymphoid cells HY Shih, G Sciumè, AC Poholek, G Vahedi, K Hirahara, AV Villarino, ... Immunological Reviews 261 (1), 23-49, 2014 | 89 | 2014 |
The transcription factor T-bet limits amplification of type I IFN transcriptome and circuitry in T helper 1 cells S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, ... Immunity 46 (6), 983-991. e4, 2017 | 82 | 2017 |
Helper T cell plasticity: impact of extrinsic and intrinsic signals on transcriptomes and epigenomes M Bonelli, HY Shih, K Hirahara, K Singelton, A Laurence, A Poholek, ... Transcriptional control of lineage differentiation in immune cells, 279-326, 2014 | 64 | 2014 |
Retinoic acid receptor alpha represses a Th9 transcriptional and epigenomic program to reduce allergic pathology DM Schwartz, TK Farley, N Richoz, C Yao, HY Shih, F Petermann, ... Immunity 50 (1), 106-120. e10, 2019 | 60 | 2019 |