| Hedgehog signaling induces osteosarcoma development through Yap1 and H19 overexpression LH Chan, W Wang, W Yeung, Y Deng, P Yuan, KK Mak Oncogene 33 (40), 4857, 2014 | 171 | 2014 |
| CRAF methylation by PRMT6 regulates aerobic glycolysis driven hepatocarcinogenesis via ERK‐dependent PKM2 nuclear relocalization and activation TL Wong, KY Ng, K Vin Tan, LH Chan, L Zhou, N Che, R LC Hoo, TK Lee, ... Hepatology, 2019 | 87 | 2019 |
| PRMT6 Regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation LH Chan, L Zhou, KY Ng, TL Wong, TK Lee, R Sharma, JH Loong, ... Cell reports 25 (3), 690-701. e8, 2018 | 81 | 2018 |
| Protein arginine methyltransferase PRMT6 regulates RAS/RAF binding and MEK/ERK-mediated cancer stemness activities in hepatocellular carcinoma through CRAF methylation LH CHAN, L Zhou, KY Ng, TL Wong, TK Lee, R Sharma, HC LOONG, ... Cell Reports, 2018 | 81* | 2018 |
| TP53INP1 downregulation activates a p73-dependent DUSP10/ERK signaling pathway to promote metastasis of hepatocellular carcinoma KY Ng, LH Chan, S Chai, M Tong, XY Guan, NP Lee, Y Yuan, D Xie, ... Cancer research 77 (17), 4602-4612, 2017 | 46 | 2017 |
| Turning hepatic cancer stem cells inside out–a deeper understanding through multiple perspectives LH Chan, ST Luk, S Ma Molecules and cells 38 (3), 202, 2015 | 45 | 2015 |
| The tumor suppressive role of PRMT6 in regulating the pathogenesis of hepatocellular carcinoma LH Chan, KY Ng, S Ma Cancer Research 75 (15 Supplement), 2333-2333, 2015 | 1 | 2015 |
| Down-regulation of PRMT6 drives Warburg effect through ERK induced relocalization of PKM2 to promote tumorigenicity and sorafenib resistance in hepatocellular carcinoma TL Wong, LH Chan, S Ma Cancer Research 79 (13 Supplement), 1852-1852, 2019 | | 2019 |
| Protein arginine methyltransferase PRMT6 regulates cancer stemness through CRAF methylation in hepatocellular carcinoma LH Chan, L Zhou, KY Ng, TL Wong, TK Lee, YP Ching, YF Yuan, D Xie, ... Cancer Research 78 (13 Supplement), 4479-4479, 2018 | | 2018 |
| Abstract LB-139: PRMT6-dependent CRAF/ERK signaling regulates cancer stem cell plasticity in liver cancer LH Chan, L Zhou, KY Ng, TL Wong, S Chai, TK Lee, XY Guan, YP Ching, ... Cancer Research 77 (13 Supplement), LB-139-LB-139, 2017 | | 2017 |
| Downregulation of PRMT6 promotes the Warburg effect in hepatocellular carcinoma via PKM2 TL Wong, LH Chan, S Ma Cancer Research 77 (13 Supplement), 5416-5416, 2017 | | 2017 |
| TP53INP1 negatively regulates ERK1/2 via p73-dependent DUSP10 expression to promote metastasis in hepatocellular carcinoma KY Ng, LH Chan, S Chai, M Tong, XY Guan, NP Lee, YF Yuan, D Xie, ... Cancer Research 77 (13 Supplement), 4842-4842, 2017 | | 2017 |
| Functional and mechanistic characterization of PRMT6 in regulating the diverse cellular properties implicated in the pathogenesis of hepatocellular carcinoma L Chan HKU Theses Online (HKUTO), 2016 | | 2016 |
| The Roles of Hedgehog Signaling in the Development of Osteosarcoma LH Chan Chinese University of Hong Kong, 2012 | | 2012 |
