| Synthesis of amide and urea derivatives of benzothiazole as Raf-1 inhibitor EY Song, N Kaur, MY Park, Y Jin, K Lee, G Kim, KY Lee, JS Yang, ... European journal of medicinal chemistry 43 (7), 1519-1524, 2008 | 94 | 2008 |
| Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation PH Cha, YH Cho, SK Lee, JH Lee, WJ Jeong, BS Moon, JH Yun, JS Yang, ... Nature chemical biology 12 (8), 593-600, 2016 | 91 | 2016 |
| Property-based optimization of hydroxamate-based γ-lactam HDAC inhibitors to improve their metabolic stability and pharmacokinetic profiles E Choi, C Lee, M Cho, JJ Seo, JS Yang, SJ Oh, K Lee, SK Park, HM Kim, ... Journal of Medicinal Chemistry 55 (23), 10766-10770, 2012 | 77 | 2012 |
| Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model Y Choi, SK Park, HM Kim, JS Kang, YD Yoon, SB Han, JW Han, JS Yang, ... Experimental & molecular medicine 40 (5), 574-581, 2008 | 69 | 2008 |
| Synthesis and biological evaluation of novel aliphatic amido-quaternary ammonium salts for anticancer chemotherapy: part I JS Yang, D Song, B Lee, WJ Ko, SK Park, M Won, K Lee, HM Kim, G Han European journal of medicinal chemistry 46 (7), 2861-2866, 2011 | 35 | 2011 |
| Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors CH Park, C Lee, JS Yang, BY Joe, K Chun, H Kim, HY Kim, JS Kang, ... Bioorganic & Medicinal Chemistry Letters 24 (12), 2655-2660, 2014 | 27 | 2014 |
| A Ras destabilizer KYA1797K overcomes the resistance of EGFR tyrosine kinase inhibitor in KRAS-mutated non-small cell lung cancer J Park, YH Cho, WJ Shin, SK Lee, JH Lee, T Kim, PH Cha, JS Yang, ... Scientific reports 9 (1), 648, 2019 | 26 | 2019 |
| Synthesis and biological evaluation of novel thieno [2, 3-d] pyrimidine-based FLT3 inhibitors as anti-leukemic agents JS Yang, CH Park, C Lee, H Kim, C Oh, Y Choi, JS Kang, J Yun, JH Jeong, ... European Journal of Medicinal Chemistry 85, 399-407, 2014 | 25 | 2014 |
| Discovery of pyridone‐based histone deacetylase inhibitors: approaches for metabolic stability M Cho, E Choi, JS Yang, C Lee, JJ Seo, BS Kim, SJ Oh, HM Kim, K Lee, ... ChemMedChem 8 (2), 272-279, 2013 | 25 | 2013 |
| A novel antitumor piperazine alkyl compound causes apoptosis by inducing RhoB expression via ROS-mediated c-Abl/p38 MAPK signaling KS Chung, G Han, BK Kim, HM Kim, JS Yang, J Ahn, K Lee, KB Song, ... Cancer chemotherapy and pharmacology 72, 1315-1324, 2013 | 21 | 2013 |
| Use of benzo-heterocycle derivatives for preventing and treating cancer or for inhibiting cancer metastasis S Kim, JW Choi, JY Lee, DG Kim, GH Han, JS Yang, CH Lee US Patent 10,130,611, 2018 | 20 | 2018 |
| Structure based optimization of chromen-based TNF-α converting enzyme (TACE) inhibitors on S1′ pocket and their quantitative structure–activity relationship (QSAR) study JS Yang, K Chun, JE Park, M Cho, J Seo, D Song, H Yoon, CH Park, ... Bioorganic & medicinal chemistry 18 (24), 8618-8629, 2010 | 18 | 2010 |
| New synthetic aliphatic sulfonamido-quaternary ammonium salts as anticancer chemotherapeutic agents D Song, JS Yang, C Oh, S Cui, BK Kim, M Won, J Lee, HM Kim, G Han European journal of medicinal chemistry 69, 670-677, 2013 | 16 | 2013 |
| Structural modifications at the 6-position of thieno [2, 3-d] pyrimidines and their effects on potency at FLT3 for treatment of acute myeloid leukemia H Kim, C Lee, JS Yang, S Choi, CH Park, JS Kang, SJ Oh, J Yun, MH Kim, ... European Journal of Medicinal Chemistry 120, 74-85, 2016 | 14 | 2016 |
| Structure-activity relationship of novel lactam based histone deacetylase inhibitors as potential anticancer drugs JS Yang, TG Chun, K Nam, HM Kim, GH Han Bulletin of the Korean Chemical Society 33 (6), 2063-2066, 2012 | 11 | 2012 |
| Design, synthesis and biological evaluation of novel aliphatic amido/sulfonamido-quaternary ammonium salts as antitumor agents D Song, JS Yang, SJ Kim, BK Kim, SK Park, M Won, K Lee, HM Kim, ... Bioorganic & medicinal chemistry 21 (3), 788-794, 2013 | 8 | 2013 |
| Discovery of orally available runt-related transcription factor 3 (RUNX3) modulators for anticancer chemotherapy by epigenetic activation and protein stabilization JS Yang, C Lee, M Cho, H Kim, JH Kim, S Choi, SJ Oh, JS Kang, ... Journal of Medicinal Chemistry 58 (8), 3512-3521, 2015 | 7 | 2015 |
| Identification of a thienopyrimidine derivatives target by a kinome and chemical biology approach C Lee, JS Yang, G Han Archives of pharmacal research 38, 1575-1581, 2015 | 1 | 2015 |
| Design and synthesis of thienopyrimidine based FLT3 inhibitors from SPC-839, a known IKK beta inhibitor C Oh, C Lee, JS Yang, H Kim, G Han ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| Design, synthesis, and biological evaluation of selective FLT3 inhibitors for the treatment of acute myeloid leukemia H Kim, JS Yang, C Lee, C Oh, G Han ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
Gyoonhee Hanprofessor of biotechnology and pharmacy, Yonsei Universityyonsei.ac.kr의 이메일 확인됨
Gyoonhee Hanprofessor of biotechnology and pharmacy, Yonsei Universityyonsei.ac.kr의 이메일 확인됨