Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1 DA Barbie, P Tamayo, JS Boehm, SY Kim, SE Moody, IF Dunn, ... Nature 462 (7269), 108-112, 2009 | 3475 | 2009 |
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations SV Sharma, DY Lee, B Li, MP Quinlan, F Takahashi, S Maheswaran, ... Cell 141 (1), 69-80, 2010 | 2817 | 2010 |
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition M Yu, A Bardia, BS Wittner, SL Stott, ME Smas, DT Ting, SJ Isakoff, ... science 339 (6119), 580-584, 2013 | 2788 | 2013 |
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis N Aceto, A Bardia, DT Miyamoto, MC Donaldson, BS Wittner, JA Spencer, ... Cell 158 (5), 1110-1122, 2014 | 2696 | 2014 |
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility M Yu, A Bardia, N Aceto, F Bersani, MW Madden, MC Donaldson, ... science 345 (6193), 216-220, 2014 | 1026 | 2014 |
RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis F Hong, R Breitling, CW McEntee, BS Wittner, JL Nemhauser, J Chory Bioinformatics 22 (22), 2825-2827, 2006 | 878 | 2006 |
A microfluidic device for label-free, physical capture of circulating tumor cell clusters AF Sarioglu, N Aceto, N Kojic, MC Donaldson, M Zeinali, B Hamza, ... Nature methods 12 (7), 685-691, 2015 | 780 | 2015 |
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance DT Miyamoto, YU Zheng, BS Wittner, RJ Lee, H Zhu, KT Broderick, ... Science 349 (6254), 1351-1356, 2015 | 748 | 2015 |
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis M Yu, DT Ting, SL Stott, BS Wittner, F Ozsolak, S Paul, JC Ciciliano, ... Nature 487 (7408), 510-513, 2012 | 576 | 2012 |
Large automatic learning, rule extraction, and generalization J Denker, D Schwartz, B Wittner, S Solla, R Howard, L Jackel, J Hopfield Complex systems 1 (5), 877-922, 1987 | 568 | 1987 |
Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells DT Ting, BS Wittner, M Ligorio, NV Jordan, AM Shah, DT Miyamoto, ... Cell reports 8 (6), 1905-1918, 2014 | 541 | 2014 |
HER2 expression identifies dynamic functional states within circulating breast cancer cells NV Jordan, A Bardia, BS Wittner, C Benes, M Ligorio, Y Zheng, M Yu, ... Nature 537 (7618), 102-106, 2016 | 425 | 2016 |
Androgen receptor signaling in circulating tumor cells as a marker of hormonally responsive prostate cancer DT Miyamoto, RJ Lee, SL Stott, DT Ting, BS Wittner, M Ulman, ME Smas, ... Cancer discovery 2 (11), 995-1003, 2012 | 334 | 2012 |
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis RY Ebright, S Lee, BS Wittner, KL Niederhoffer, BT Nicholson, A Bardia, ... Science 367 (6485), 1468-1473, 2020 | 320 | 2020 |
Association of valproate‐induced teratogenesis with histone deacetylase inhibition in vivo N Gurvich, MG Berman, BS Wittner, RC Gentleman, PS Klein, JBA Green The FASEB journal 19 (9), 1166-1168, 2005 | 229 | 2005 |
MYC regulation of a ¡°poor-prognosis¡± metastatic cancer cell state A Wolfer, BS Wittner, D Irimia, RJ Flavin, M Lupien, RN Gunawardane, ... Proceedings of the National Academy of Sciences 107 (8), 3698-3703, 2010 | 215 | 2010 |
Identification of a pharmacologically tractable Fra-1/ADORA2B axis promoting breast cancer metastasis CJ Desmet, T Gallenne, A Prieur, F Reyal, NL Visser, BS Wittner, MA Smit, ... Proceedings of the National Academy of Sciences 110 (13), 5139-5144, 2013 | 203 | 2013 |
Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort BS Wittner, DC Sgroi, PD Ryan, TJ Bruinsma, AM Glas, A Male, S Dahiya, ... Clinical Cancer Research 14 (10), 2988-2993, 2008 | 183 | 2008 |
Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer F Bersani, E Lee, PV Kharchenko, AW Xu, M Liu, K Xega, OC MacKenzie, ... Proceedings of the National Academy of Sciences 112 (49), 15148-15153, 2015 | 178 | 2015 |
The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis X Hong, W Roh, RJ Sullivan, KHK Wong, BS Wittner, H Guo, TD Dubash, ... Cancer Discovery 11 (3), 678-695, 2021 | 170 | 2021 |