Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors HVT Nguyen, Q Chen, JT Paletta, P Harvey, Y Jiang, H Zhang, MD Boska, ... ACS central science 3 (7), 800-811, 2017 | 151 | 2017 |
Tailored silyl ether monomers enable backbone-degradable polynorbornene-based linear, bottlebrush and star copolymers through ROMP P Shieh, HVT Nguyen, JA Johnson Nature chemistry 11 (12), 1124-1132, 2019 | 144 | 2019 |
Iterative exponential growth synthesis and assembly of uniform diblock copolymers Y Jiang, MR Golder, HVT Nguyen, Y Wang, M Zhong, JC Barnes, ... Journal of the American Chemical Society 138 (30), 9369-9372, 2016 | 130 | 2016 |
Robust gold nanorods stabilized by bidentate N-heterocyclic-carbene–thiolate ligands MJ MacLeod, AJ Goodman, HZ Ye, HVT Nguyen, T Van Voorhis, ... Nature chemistry 11 (1), 57-63, 2019 | 115 | 2019 |
Triply loaded nitroxide brush-arm star polymers enable metal-free millimetric tumor detection by magnetic resonance imaging HVT Nguyen, A Detappe, NM Gallagher, H Zhang, P Harvey, C Yan, ... ACS nano 12 (11), 11343-11354, 2018 | 69 | 2018 |
Stereochemical Sequence Dictates Unimolecular Diblock Copolymer Assembly MR Golder, Y Jiang, PE Teichen, HVT Nguyen, W Wang, N Milos, ... Journal of the American Chemical Society 140 (5), 1596-1599, 2018 | 69 | 2018 |
Polyoxazoline-Based Bottlebrush and Brush-Arm Star Polymers via ROMP: Syntheses and Applications as Organic Radical Contrast Agents GG Alvaradejo, HVT Nguyen, P Harvey, NM Gallagher, D Le, MF Ottaviani, ... ACS Macro Letters 8 (4), 473-478, 2019 | 64 | 2019 |
Using an RNAi signature assay to guide the design of three-drug-conjugated nanoparticles with validated mechanisms, in vivo efficacy, and low toxicity JC Barnes, PM Bruno, HVT Nguyen, L Liao, J Liu, MT Hemann, ... Journal of the American Chemical Society 138 (38), 12494-12501, 2016 | 57 | 2016 |
Scalable Synthesis of Multivalent Macromonomers for ROMP HVT Nguyen, NM Gallagher, F Vohidov, Y Jiang, K Kawamoto, H Zhang, ... ACS Macro Letters 7 (4), 472-476, 2018 | 54 | 2018 |
ABC triblock bottlebrush copolymer-based injectable hydrogels: design, synthesis, and application to expanding the therapeutic index of cancer immunochemotherapy F Vohidov, LE Milling, Q Chen, W Zhang, S Bhagchandani, HVT Nguyen, ... Chemical Science 11 (23), 5974-5986, 2020 | 53 | 2020 |
Bottlebrush polymers with flexible enantiomeric side chains display differential biological properties HVT Nguyen, Y Jiang, S Mohapatra, W Wang, JC Barnes, NJ Oldenhuis, ... Nature Chemistry 14 (1), 85-93, 2022 | 52 | 2022 |
Mikto-Brush-Arm Star Polymers via Cross-Linking of Dissimilar Bottlebrushes: Synthesis and Solution Morphologies Y Shibuya, HVT Nguyen, JA Johnson ACS Macro Letters 6 (9), 963-968, 2017 | 49 | 2017 |
Molecular bottlebrush prodrugs as mono-and triplex combination therapies for multiple myeloma A Detappe, HVT Nguyen, Y Jiang, MP Agius, W Wang, C Mathieu, NK Su, ... Nature nanotechnology 18 (2), 184-192, 2023 | 32 | 2023 |
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs MR Golder, J Liu, JN Andersen, MV Shipitsin, F Vohidov, HVT Nguyen, ... Nature biomedical engineering 2 (11), 822-830, 2018 | 31 | 2018 |
Synthetic Glycomacromolecules of Defined Valency, Absolute Configuration, and Topology Distinguish between Human Lectins M Hartweg, Y Jiang, G Yilmaz, CM Jarvis, HVT Nguyen, GA Primo, ... JACS Au 1 (10), 1621-1630, 2021 | 29 | 2021 |
Antibody-targeting of ultra-small nanoparticles enhances imaging sensitivity and enables longitudinal tracking of multiple myeloma A Detappe, M Reidy, Y Yu, C Mathieu, HVT Nguyen, TP Coroller, F Lam, ... Nanoscale 11 (43), 20485-20496, 2019 | 29 | 2019 |
Design of BET Inhibitor Bottlebrush Prodrugs with Superior Efficacy and Devoid of Systemic Toxicities F Vohidov, JN Andersen, KD Economides, MV Shipitsin, O Burenkova, ... Journal of the American Chemical Society 143 (12), 4714-4724, 2021 | 25 | 2021 |
Brush-First and ROMP-Out with Functional (Macro) monomers: Method Development, Structural Investigations, and Applications of an Expanded Brush-Arm Star Polymer Platform MR Golder, HVT Nguyen, NJ Oldenhuis, J Grundler, EJ Park, JA Johnson Macromolecules 51 (23), 9861-9870, 2018 | 24 | 2018 |
Pro-organic radical contrast agents (“pro-ORCAs”) for real-time MRI of pro-drug activation in biological systems HVT Nguyen, A Detappe, P Harvey, N Gallagher, C Mathieu, MP Agius, ... Polymer Chemistry 11 (29), 4768-4779, 2020 | 22 | 2020 |
Main-Chain Zwitterionic Supramolecular Polymers Derived from N-Heterocyclic Carbene–Carbodiimide (NHC–CDI) Adducts NM Gallagher, AV Zhukhovitskiy, HVT Nguyen, JA Johnson Macromolecules 51 (8), 3006-3016, 2018 | 18 | 2018 |